transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2011-0-4-41-46transplantologiya-323Research ArticleСЛУЧАЙ ИЗ ПРАКТИКИCASE REPORTСлучай аппаратной перфузии почки как детектор ошибки действий персонала. Перфузионное "излечение" отека трансплантатаA case of the kidney apparatus perfusion as a detector of errors in personnel actions. A graft edema “cure” by perfusionБагненкоС. Ф.BagnenkoS. F.МойсюкЯ. Г.MoysiukYa. G.СкворцовА. Е.SkvortzovA. E.РезникА. О.ReznikA. O.АнаньевА. Н.AnanyevA. N.РезникО. Н.ReznikO. N.onreznik@yahoo.comНаучно-исследовательский институт скорой помощи им. И. И. ДжанелидзеRussian FederationФГУ «Федеральный научный центр трансплантологии и искусственных органов им. акад. В.И. Шумакова» Минздравсоцразвития РФRussian Federation201121082018044146Copyright © Багненко С.Ф., Мойсюк Я.Г., Скворцов А.Е., Резник А.О., Ананьев А.Н., Резник О.Н., 20182018Багненко С.Ф., Мойсюк Я.Г., Скворцов А.Е., Резник А.О., Ананьев А.Н., Резник О.Н.Bagnenko S.F., Moysiuk Y.G., Skvortzov A.E., Reznik A.O., Ananyev A.N., Reznik O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/323

Дефицит донорских органов, лишь усугубляющийся с течением времени, вынуждает трансплантационное сообщество на поиски дополнительных источников донорских органов, одним из которых являются доноры с необратимой остановкой кровообращения, широко используемые в настоящее время во всем мире. Не секрет, что органы, полученные от таких доноров, отнюдь не идеального качества, поэтому для улучшения исходов таких трансплантаций было разработано несколько методов. Аппаратная перфузия представляется перспективным способом, позволяющим проводить селекцию, реабилитацию и лечение почек, полученных от доноров с расширенными критериями, однако точный механизм этих воздействий до сих пор полностью не изучен. В описанном клиническом случае мы предпринимаем попытку пролить свет на существо этих процессов.

Utilization of kidneys donated from uncontrolled donors after cardiac death (UDCD) became an additional source of organs for transplantation worldwide in the light of ongoing global organ shortage. Machine perfusion proven to be a promising perspective for selection, rehabilitation and treatment of kidneys from expanded criteria donors, however, exact mechanisms of these effects remains unclear. On presented clinical case we are trying to clarify the essence of them. In 2006-2007 a pilot study was carried out by our team for use of machine perfusion to perform selection of kidney obtained from UDCD and improve their quality. According to study design each couple of grafts were divided and transplanted to different recipients. During ordinary procedure a staff mistake occurred, which, fortunately, helped us to understand one of the treatment mechanisms of hypothermic machine perfusion.

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The authors declare that there are no conflicts of interest present.