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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transplantologiya</journal-id><journal-title-group><journal-title xml:lang="ru">Трансплантология</journal-title><trans-title-group xml:lang="en"><trans-title>Transplantologiya. The Russian Journal of Transplantation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0506</issn><issn pub-type="epub">2542-0909</issn><publisher><publisher-name>IPO Association of Transplantologists</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">transplantologiya-33</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОБЛЕМНЫЕ АСПЕКТЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROBLEMATIC ASPECTS</subject></subj-group></article-categories><title-group><article-title>Передача инфекционных возбудителей от органов донора реципиенту. Нужны ли изменения в оценке рисков?</article-title><trans-title-group xml:lang="en"><trans-title>Transmission of infectious agents from the donor to the recipient. Do we need change in the risk assessment?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавель</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravel</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">zhsergey5@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>N. K.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черненькая</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernenkaya</surname><given-names>T. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уткина</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Utkina</surname><given-names>I. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>31</day><month>01</month><year>2016</year></pub-date><volume>0</volume><issue>1</issue><fpage>7</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Журавель С.В., Кузнецова Н.К., Черненькая Т.В., Уткина И.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Журавель С.В., Кузнецова Н.К., Черненькая Т.В., Уткина И.И.</copyright-holder><copyright-holder xml:lang="en">Zhuravel S.V., Kuznetsova N.K., Chernenkaya T.V., Utkina I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jtransplantologiya.ru/jour/article/view/33">https://www.jtransplantologiya.ru/jour/article/view/33</self-uri><abstract><p>В статье обсуждаются возможные риски заражения реципиента бактериальными, грибковыми и вирусными инфекциями посредством донорских органов. Определены инфекционные заболевания, при которых изъятие донорских органов для реципиента противопоказано, и те заболевания, при которых донорские органы можно использовать.</p></abstract><trans-abstract xml:lang="en"><p>The article discusses the possible risks of infection by bacterial, fungal and viral infections the recipient of donor organs. Identified infectious diseases in which the reserve of donor organs is contraindicated for the recipient and the diseases for which it is possible to use donor organs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>донорство органов</kwd><kwd>передача инфекционных заболеваний</kwd><kwd>бактериальные и грибковые инфекции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>organ donation</kwd><kwd>transmission of infectious diseases</kwd><kwd>bacterial and fungal infections</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Intensivist-led management of braindead donors is associated with an increase in organ recovery for transplantation / K. Singbart, R. Murugan, A.M. Kaynar, et al. // Am. J. Transplant. 2008. – Vol.11, N.7. – P.1517–1521.</mixed-citation><mixed-citation xml:lang="en">Intensivist-led management of braindead donors is associated with an increase in organ recovery for transplantation / K. Singbart, R. Murugan, A.M. Kaynar, et al. // Am. J. Transplant. 2008. – Vol.11, N.7. – P.1517–1521.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Organ donation for transplantation: improving donor identification and consent rates for deceased organ donation / National Institute for Health and Clinical Excellence. – 2011. – Режим доступа: http://guidance.nice.org.uk/CG135</mixed-citation><mixed-citation xml:lang="en">Organ donation for transplantation: improving donor identification and consent rates for deceased organ donation / National Institute for Health and Clinical Excellence. – 2011. – Режим доступа: http://guidance.nice.org.uk/CG135</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Interim Results of a National Test of the Rapid Assessment of Hospital Procurement Barriers in Donation (RAPiD) / H.M. Traino, G.P. Adolod, T. Shafer, L.A. Siminoff // Am. J. Transplant. – 2012. – Vol. 12, N.11. – P.3094–3103.</mixed-citation><mixed-citation xml:lang="en">Interim Results of a National Test of the Rapid Assessment of Hospital Procurement Barriers in Donation (RAPiD) / H.M. Traino, G.P. Adolod, T. Shafer, L.A. Siminoff // Am. J. Transplant. – 2012. – Vol. 12, N.11. – P.3094–3103.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Посмертное донорство: Национальные клинические рекомендации. 2013. – Режим доступа: http://transpl.ru/images/cms/data/pdf/nacional_nye_klinicheskie_rekomendacii_posmertnoe_donorstvo_organov.pdf (In Russian). Posmertnoe donorstvo: Natsional'nye klinicheskie rekomendatsii. [Posthumous donation: National clinical guidelines]. 2013. Available at: http://transpl.ru/images/cms/data/pdf/nacional_nye_klinicheskie_rekomendacii_posmertnoe_donorstvo_organov.pdf (In Russian).</mixed-citation><mixed-citation xml:lang="en">Посмертное донорство: Национальные клинические рекомендации. 2013. – Режим доступа: http://transpl.ru/images/cms/data/pdf/nacional_nye_klinicheskie_rekomendacii_posmertnoe_donorstvo_organov.pdf (In Russian). Posmertnoe donorstvo: Natsional'nye klinicheskie rekomendatsii. [Posthumous donation: National clinical guidelines]. 2013. Available at: http://transpl.ru/images/cms/data/pdf/nacional_nye_klinicheskie_rekomendacii_posmertnoe_donorstvo_organov.pdf (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Журавель, С.В. Проблема системного кандидоза после трансплантации солидных органов. Обзор литературы / С.В. Журавель, А.О. Чугунов, Т.В. Черненькая // Трансплантология. – 2012. – № 3. – С.42–48. Zhuravel' S.V., Chugunov A.O., Chernen'kaya T.V. Problema sistemnogo kandidoza posle transplantatsii solidnykh organov. Obzor literatury. [The problem of systemic candidiasis after solid organ transplantation. Review of the literature]. Transplantologiya. 2012; 3: 42–48. (In Russian).</mixed-citation><mixed-citation xml:lang="en">Журавель, С.В. Проблема системного кандидоза после трансплантации солидных органов. Обзор литературы / С.В. Журавель, А.О. Чугунов, Т.В. Черненькая // Трансплантология. – 2012. – № 3. – С.42–48. Zhuravel' S.V., Chugunov A.O., Chernen'kaya T.V. Problema sistemnogo kandidoza posle transplantatsii solidnykh organov. Obzor literatury. [The problem of systemic candidiasis after solid organ transplantation. Review of the literature]. Transplantologiya. 2012; 3: 42–48. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Transmission of Elizabethkingia meningoseptica (formerly Chryseobacterium meningosepticum) to tissueallograft recipients: a report of two cases / E.J. Cartwright, R.M. Prabhu, C.E. Zinderman, et al. // J. Bone Joint Surg. Am.- 2010. – Vol. 92, N.6. – P.1501– 1506.</mixed-citation><mixed-citation xml:lang="en">Transmission of Elizabethkingia meningoseptica (formerly Chryseobacterium meningosepticum) to tissueallograft recipients: a report of two cases / E.J. Cartwright, R.M. Prabhu, C.E. Zinderman, et al. // J. Bone Joint Surg. Am.- 2010. – Vol. 92, N.6. – P.1501– 1506.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Eastlund, T. Infectious disease transmission through cell, tissue, and organ transplantation: reducing the risk through donor selection / T. Eastlund // Cell. Transplant. – 1995. – Vol. 4, N.5. – P. 455–477.</mixed-citation><mixed-citation xml:lang="en">Eastlund, T. Infectious disease transmission through cell, tissue, and organ transplantation: reducing the risk through donor selection / T. Eastlund // Cell. Transplant. – 1995. – Vol. 4, N.5. – P. 455–477.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Greenwald, M.A. Infectious Disease Transmission during Organ and Tissue Transplantation / M.A. Greenwald, M.J. Kuehnert, J.A. Fishman // Emerg. Infect. Dis. – 2012. – Vol. 18, N.8. – P.e1.</mixed-citation><mixed-citation xml:lang="en">Greenwald, M.A. Infectious Disease Transmission during Organ and Tissue Transplantation / M.A. Greenwald, M.J. Kuehnert, J.A. Fishman // Emerg. Infect. Dis. – 2012. – Vol. 18, N.8. – P.e1.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Donor-derived disease transmission events in the United States: data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee / M.G. Ison, J. Hager, E. Blumberg, et al. // Am. J. Transplant. – 2009. – Vol. 9,N.8. – P. 1929–1935.</mixed-citation><mixed-citation xml:lang="en">Donor-derived disease transmission events in the United States: data reviewed by the OPTN/UNOS Disease Transmission Advisory Committee / M.G. Ison, J. Hager, E. Blumberg, et al. // Am. J. Transplant. – 2009. – Vol. 9,N.8. – P. 1929–1935.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Mortality associated with carbapenemresistant Klebsiella pneumoniae infections in liver transplant recipients / J.S. Kalpoe, E. Sonnenberg, S.H. Factor, et al. // Liver Transpl. – 2012. – Vol. 18, N.4. – P. 468–474.</mixed-citation><mixed-citation xml:lang="en">Mortality associated with carbapenemresistant Klebsiella pneumoniae infections in liver transplant recipients / J.S. Kalpoe, E. Sonnenberg, S.H. Factor, et al. // Liver Transpl. – 2012. – Vol. 18, N.4. – P. 468–474.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Organ transplantation from a donor colonized with a multidrug-resistant organism: a case report / E. Goldberg, J. Bishara, S. Lev, et al. // Transpl. Infect. Dis. – 2012. – Vol. 14, N.3. – P. 296–299.</mixed-citation><mixed-citation xml:lang="en">Organ transplantation from a donor colonized with a multidrug-resistant organism: a case report / E. Goldberg, J. Bishara, S. Lev, et al. // Transpl. Infect. Dis. – 2012. – Vol. 14, N.3. – P. 296–299.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Donors with positive blood culture: could they transmit infections to the recipients? / C. González-Segura, M. Pascua, G.L. Huete, et al. // Transplant. Proc. – 2005. – Vol. 37, N.9. – P. 3664–3666.</mixed-citation><mixed-citation xml:lang="en">Donors with positive blood culture: could they transmit infections to the recipients? / C. González-Segura, M. Pascua, G.L. Huete, et al. // Transplant. Proc. – 2005. – Vol. 37, N.9. – P. 3664–3666.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Is serological evidence of infection with syphilis a contraindication to kidney donation? Case report and review of the literature / L.J. Gibel, W. Sterling, W. Hoy, A. Harford // J. Urol. – 1987. – Vol. 138, N.5. – P. 1226–1227.</mixed-citation><mixed-citation xml:lang="en">Is serological evidence of infection with syphilis a contraindication to kidney donation? Case report and review of the literature / L.J. Gibel, W. Sterling, W. Hoy, A. Harford // J. Urol. – 1987. – Vol. 138, N.5. – P. 1226–1227.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Возможности использования инфицированных трупных доноров для выполнения трансплантации печени / А.С. Ермолов, А.В. Чжао, В.А. Гуляев и др. // Хирургия. – 2006. – № 3. – С. 72–77. Ermolov A.S., Chzhao A.V., Gulyaev V.A., et al. Vozmozhnosti ispol'zovaniya infitsirovannykh trupnykh donorov dlya vypolneniya transplantatsii pecheni. [The possibility of using infected cadaver donors to perform liver transplantation]. Khirurgiya. 2006; 3: 72–77. (In Russian).</mixed-citation><mixed-citation xml:lang="en">Возможности использования инфицированных трупных доноров для выполнения трансплантации печени / А.С. Ермолов, А.В. Чжао, В.А. Гуляев и др. // Хирургия. – 2006. – № 3. – С. 72–77. Ermolov A.S., Chzhao A.V., Gulyaev V.A., et al. Vozmozhnosti ispol'zovaniya infitsirovannykh trupnykh donorov dlya vypolneniya transplantatsii pecheni. [The possibility of using infected cadaver donors to perform liver transplantation]. Khirurgiya. 2006; 3: 72–77. (In Russian).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Successful transplantation of organs retricvid from a donor with syphilis / F. Caballero, P. Domingo, N. Rabella, A. Lopez – Navidad // Transplantation. – 1998. – Vol. 65. – P. 598–599.</mixed-citation><mixed-citation xml:lang="en">Successful transplantation of organs retricvid from a donor with syphilis / F. Caballero, P. Domingo, N. Rabella, A. Lopez – Navidad // Transplantation. – 1998. – Vol. 65. – P. 598–599.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Prevention of de novo hepatitis B infection in recipients of hepatic allografts from anti-HBc positive donors / S.F. Dodson, C.A. Bonham, D.A. Celler, et al. // Transplantation. – 1999. – Vol. 68, N.7. – P. 1058–1061.</mixed-citation><mixed-citation xml:lang="en">Prevention of de novo hepatitis B infection in recipients of hepatic allografts from anti-HBc positive donors / S.F. Dodson, C.A. Bonham, D.A. Celler, et al. // Transplantation. – 1999. – Vol. 68, N.7. – P. 1058–1061.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation / S. Saab, A.J. Chang, S. Comulaba, et al. // Liver Transpl. – 2003. – Vol. 9, N.10. – Р. 1053–1061.</mixed-citation><mixed-citation xml:lang="en">Outcomes of hepatitis C- and hepatitis B core antibody-positive grafts in orthotopic liver transplantation / S. Saab, A.J. Chang, S. Comulaba, et al. // Liver Transpl. – 2003. – Vol. 9, N.10. – Р. 1053–1061.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Rodriguez-Luna, H. Management of Hepatitis C Virus Infection in the Setting of Liver Transplantation / H. Rodriguez-Luna, H.E. Vargas // Liver Transpl. – 2005. – Vol. 11, N.5. – P. 479–489.</mixed-citation><mixed-citation xml:lang="en">Rodriguez-Luna, H. Management of Hepatitis C Virus Infection in the Setting of Liver Transplantation / H. Rodriguez-Luna, H.E. Vargas // Liver Transpl. – 2005. – Vol. 11, N.5. – P. 479–489.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Liver transplantation with hepatitis C virus-infected graft: interaction between donor and recipient viral strains / X. Fan,</mixed-citation><mixed-citation xml:lang="en">Liver transplantation with hepatitis C virus-infected graft: interaction between donor and recipient viral strains / X. Fan,</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">D.M. Lang, Y. Xu, et al. // Hepatology. – 2003. – Vol. 38, N.1. – P.25–33.</mixed-citation><mixed-citation xml:lang="en">D.M. Lang, Y. Xu, et al. // Hepatology. – 2003. – Vol. 38, N.1. – P.25–33.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Transplantation of hepatitis C-positive livers in hepatitis C-positive patients is equivalent to transplanting hepatitis C-negative livers / C.E. Marroquin, G. Marino, P.C. Kuo, et al. // Liver Transplant. – 2001. – Vol. 7, N.9. – P.762– 768.</mixed-citation><mixed-citation xml:lang="en">Transplantation of hepatitis C-positive livers in hepatitis C-positive patients is equivalent to transplanting hepatitis C-negative livers / C.E. Marroquin, G. Marino, P.C. Kuo, et al. // Liver Transplant. – 2001. – Vol. 7, N.9. – P.762– 768.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">West Nile virus transmission via organ transplantation and blood transfusion–Louisiana, 2008 / Centers for Disease Control and Prevention // MMWR Morb. Mortal Wkly Rep. – 2009. – Vol. 58, N.45. – P. 1263–1267.</mixed-citation><mixed-citation xml:lang="en">West Nile virus transmission via organ transplantation and blood transfusion–Louisiana, 2008 / Centers for Disease Control and Prevention // MMWR Morb. Mortal Wkly Rep. – 2009. – Vol. 58, N.45. – P. 1263–1267.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Fishman J.A. Organ and tissue safety workshop 2007: advances and challenges / J.A. Fishman, D.M. Strong, M.J. Kuehnert // Cell Tissue Bank. – 2009. – Vol. 10, N.3. – P. 271–280.</mixed-citation><mixed-citation xml:lang="en">Fishman J.A. Organ and tissue safety workshop 2007: advances and challenges / J.A. Fishman, D.M. Strong, M.J. Kuehnert // Cell Tissue Bank. – 2009. – Vol. 10, N.3. – P. 271–280.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
