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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transplantologiya</journal-id><journal-title-group><journal-title xml:lang="ru">Трансплантология</journal-title><trans-title-group xml:lang="en"><trans-title>Transplantologiya. The Russian Journal of Transplantation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0506</issn><issn pub-type="epub">2542-0909</issn><publisher><publisher-name>IPO Association of Transplantologists</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">transplantologiya-36</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Ведение потенциального донора со смертью мозга (часть 2)</article-title><trans-title-group xml:lang="en"><trans-title>Management of a potential donor with brain death (part 2)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виноградов</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinogradov</surname><given-names>V. L.</given-names></name></name-alternatives><email xlink:type="simple">v.l.vinogradov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ГНЦ ФМБЦ им. А.И. Бурназяна ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>31</day><month>01</month><year>2016</year></pub-date><volume>0</volume><issue>1</issue><fpage>41</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Виноградов В.Л., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Виноградов В.Л.</copyright-holder><copyright-holder xml:lang="en">Vinogradov V.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jtransplantologiya.ru/jour/article/view/36">https://www.jtransplantologiya.ru/jour/article/view/36</self-uri><abstract><p>После диагностики смерти мозга кондиционирование донора является продолжением предшествующей интенсивной терапии. В статье рассматриваются стандарты ведения доноров со смертью мозга, построенные на основе физиологически оправданного активного подхода.</p><p>Основными элементами протокола являются инвазивный мониторинг центральной и периферической гемодинамики, коррекция гемодинамических нарушений, коррекция гипотермии, использование гормональной терапии и адекватная ИВЛ.</p><p>Активное или даже агрессивное ведение донора со смертью мозга позволяет управлять пато физиологическими процессами и корригировать их, тем самым увеличивая число и улучшая функциональное состояние донорских органов.</p></abstract><trans-abstract xml:lang="en"><p>After the diagnosis of brain death has been made, the donor management is a continuation of the previous intensive care. The paper reviews the brain death donor management standards established on the basis of a physiologically justified active approach.</p><p>The maim elements of the donor management protocol include the invasive monitoring of the central and peripheral hemodynamic parameters, the correction of hemodynamic impairments, and hypothermia, the use of hormonal therapy, an adequate mechanical lung ventilation.</p><p>An active or even aggressive brain death donor management allows the control and correction of pathophysiological processes, thereby increasing the number and improving the functional state of donor organs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>донор со смертью мозга</kwd><kwd>ведение донора со смертью мозга</kwd><kwd>трансплантация</kwd><kwd>интенсивная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brain death donor</kwd><kwd>brain death donor management</kwd><kwd>transplantation</kwd><kwd>intensive care</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Organ donor management in Canada: recommendations of the forum on medical management to optimize donor organ potential / S.D. 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