transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2012-0-1-2-33-37transplantologiya-376Research ArticleПРОБЛЕМНЫЕ АСПЕКТЫPROBLEMATIC ASPECTSПрофилактика и лечение сосудистых осложнений после трансплантации печениProphylaxis end treatment of vascular complications after liver transplantationЖуравельС. В.ZhuravelS. V.sjuravel@rambler.ruАндрейцеваО. И.AndreytsevaO. I.ДоноваЛ. В.DonovaL. V.ДжаграевК. Р.DzhagraevK. R.ЧжаоА. В.ChzhaoA. V.НИИ СП им. Н.В. СклифосовскогоРоссияSklifosovsky Research Institute for Emergency MedicineRussian Federation20122408201801-23337Copyright © Журавель С.В., Андрейцева О.И., Донова Л.В., Джаграев К.Р., Чжао А.В., 20182018Журавель С.В., Андрейцева О.И., Донова Л.В., Джаграев К.Р., Чжао А.В.Zhuravel S.V., Andreytseva O.I., Donova L.V., Dzhagraev K.R., Chzhao A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/376

В проведенном исследовании анализируются причины развития сосудистых осложнений, их профилактика и лечение печени. В ретроспективное исследование были включены 206 пациентов, перенесших 214 ортотопических трансплантаций печени (ОТП). Сосудистые осложнения диагностированы у 18 (8,4 %) пациентов, относительно низкий уровень тромбоза печеночной артерии – в 1,4 %. Отмечается большая роль профилактики низкомолекулярным гепарином и эффективность ультразвуковой допплерографии (УЗДГ) как неинвазивного метода выявления сосудистых осложнений. Ранняя диагностика позволяет своевременно принять решение о тактике ведения пациентов, в том числе выставить показания к оперативному лечению и сохранить печеночный трансплантат.

The study analyzes the reasons for the development of vascular complications, prevention and treatment after liver transplantation. In a retrospective study enrolled 206 patients who had undergone 214 orthotopic liver transplantation (OLT). Vascular complications has diagnosed in 18 (8.4 %) patients in postoperative period. A relatively low incidence of hepatic artery thrombosis (HAT) had seen in our study. Low molecular weight heparin (LMWH) plays an important role in the prevention of thrombosis. Doppler ultrasonography is a convenient and efficient method for detecting posttransplant complications and plays an important role in guiding treatment. Early diagnosis of these complications allows to decide on the tactics of the patients and to determine indications for emergency surgical revascularization and save the graft.

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The authors declare that there are no conflicts of interest present.