transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2012-0-1-2-38-42transplantologiya-377Research ArticleПРОБЛЕМНЫЕ АСПЕКТЫPROBLEMATIC ASPECTSРоль постреперфузионного синдрома в формировании послеоперационных осложнений ортотопической трансплантации печениRole of postreperfusion syndrome in the formation of postoperative complications after orthotopic liver transplantationКиселеваЕ. А.KiseliovaE. A.

Отделение анестезиологии-реанимации

Department of Anesthesiology-Resuscitation

КимЭ. Ф.KimE. F.

Отделение трансплантации печени

Department of Liver Transplantation

УшаковаИ. А.UshakovaI. A.

Отделение анестезиологии-реанимации I

Department of Anesthesiology-Resuscitation-I

МатвеевГ. П.MatveevG. P.

Отделение анестезиологии-реанимации I

Department of Anesthesiology-Resuscitation-I

ВабищевичА. В.VabishchevichA. V.

Отделение анестезиологии-реанимации I

Department of Anesthesiology-Resuscitation-I

ГКБ № 61РоссияClinical Hospital № 61Russian FederationРНЦХ им. акад. Б.В. Петровского РАМНРоссияRSCS named after academician B.V. Petrovsky of Academy of Medical SciencesRussian Federation20122408201801-23842Copyright © Киселева Е.А., Ким Э.Ф., Ушакова И.А., Матвеев Г.П., Вабищевич А.В., 20182018Киселева Е.А., Ким Э.Ф., Ушакова И.А., Матвеев Г.П., Вабищевич А.В.Kiseliova E.A., Kim E.F., Ushakova I.A., Matveev G.P., Vabishchevich A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/377

В ретроспективном исследовании проанализировано влияние постреперфузионного синдрома на результаты ортотопической трансплантации печени 100 пациентов, которым была выполнена ортотопическая трансплантация печени от живых родственных доноров, а также 12 реципиентов, которым была выполнена ретрансплантация печени. Между группами с постреперфузионным синдромом и без него отсутствовали статистически значимые различия в динамике лактата, уровней специфических ферментов, концентрации креатинина на 3-и сут после операции, а также в продолжительности послеоперационной ИВЛ. Не было обнаружено влияния развития ПРС на функциональное состояние трансплантата и течение раннего послеоперационного периода.

The influence of postreperfusion syndrome on the results of orthotopic liver transplantation in 100 patients who underwent to liver transplantation from living related donors and 12 recipients who underwent to retransplantation of the liver was analyzed in the retrospective study. No statistically significant differences in the dynamics of lactate levels of specific enzymes, creatinine concentration at the third postoperative day, and duration of postoperative mechanical ventilation were detected between groups with and without the postreperfusion syndrome. In this retrospective observational study there was found no effect of postreperfusion syndrome on the functional state of the transplant and on the early postoperative course.

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The authors declare that there are no conflicts of interest present.