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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transplantologiya</journal-id><journal-title-group><journal-title xml:lang="ru">Трансплантология</journal-title><trans-title-group xml:lang="en"><trans-title>Transplantologiya. The Russian Journal of Transplantation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0506</issn><issn pub-type="epub">2542-0909</issn><publisher><publisher-name>IPO Association of Transplantologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23873/2074-0506-2019-11-4-290-300</article-id><article-id custom-type="elpub" pub-id-type="custom">transplantologiya-461</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНЫЕ ВОПРОСЫ ТРАНСПЛАНТОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACTUAL ISSUES OF TRANSPLANTATION</subject></subj-group></article-categories><title-group><article-title>Параметры системы окислительно-восстановительного гомеостаза у женщин с опухолями репродуктивной системы после трансплантации органов на фоне гипербарической оксигенации</article-title><trans-title-group xml:lang="en"><trans-title>Parameters of the oxidative-reduction system of the homeostasis in female transplant patients with tumors of the reproductive system treated with hyperbaric oxygen therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5342-8268</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабкина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Babkina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Васильевна Бабкина канд. мед. наук, доцент кафедры трансплантологии и искусственных органов, врач-гинеколог отделения экстренной гинекологии127473, Россия, Москва, ул. Делегатская, д. 20, стр. 1;129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Anna V. Babkina Cand. Med. Sci., Associate Professor of the Department of Transplantology and Artificial Organs, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Gynecologist of the Urgent Gynecology Department</p><p>1 Bldg. 20 Delegatskaya St., Moscow 127473 Russia;3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><email xlink:type="simple">babkina.anya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0746-1884</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хубутия</surname><given-names>М. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Khubutiya</surname><given-names>M. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Могели Шалвович Хубутия акад. РАН, проф., д-р мед. наук, заведующий кафедрой трансплантологии и искусственных органов ФГБОУ ВО МГМСУ им. А.И. Евдокимова МЗ РФ, президент ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</p></bio><bio xml:lang="en"><p>Mogeli Sh. Khubutiya Acad. of RAS, Prof., Dr. Med. Sci., Head of the Department of Transplantology and Artificial Organs, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, President of N.V. Sklifosovsky Research Institute for Emergency Medicine</p><p>1 Bldg. 20 Delegatskaya St., Moscow 127473 Russia;3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4811-0845</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левина</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levina</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Аркадьевна Левина канд. мед. наук, ведущий научный сотрудник клиники неотложной нейрохирургии</p><p>129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Olga A. Levina Cand. Med. Sci., Leading Researcher of Urgent Neurosurgery Clinic</p><p>3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0832-3272</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсеев</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Evseev</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анатолий Константинович Евсеев д-р хим. наук, ведущий научный сотрудник отделения общей реанимации</p><p>129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Anatoliy K. Evseev Dr. Chem. Sci., Leading Researcher of the General Intensive Care Unit</p><p>3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3417-2682</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабанов</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabanov</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аслан Курбанович Шабанов д-р мед. наук, старший научный сотрудник отделения общей реанимации</p><p>129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Aslan K. Shabanov Dr. Med. Sci., Leading Researcher of the General Intensive Care Unit</p><p>3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0113-306X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горончаровская</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Goroncharovskaya</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Викторовна Горончаровская канд. хим. наук, старший научный сотрудник отделения общей реанимации</p><p>129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Irina V. Goroncharovskaya Cand. Chem. Sci., Senior Researcher of the General Intensive Care Unit</p><p>3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8431-8574</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Александрович Медведев врач акушер-гинеколог, заведующий отделением гинекологии</p><p>129090, Россия, Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>Aleksandr A. Medvedev Obstetrician-Gynecologist, Head of the Urgent Gynecology Department</p><p>3 Bolshaya Sukharevskaya Sq., Moscow, 129090</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО МГМСУ им. А.И. Евдокимова МЗ РФ;&#13;
ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry;&#13;
N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2019</year></pub-date><volume>11</volume><issue>4</issue><fpage>290</fpage><lpage>300</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бабкина А.В., Хубутия М.Ш., Левина О.А., Евсеев А.К., Шабанов А.К., Горончаровская И.В., Медведев А.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Бабкина А.В., Хубутия М.Ш., Левина О.А., Евсеев А.К., Шабанов А.К., Горончаровская И.В., Медведев А.А.</copyright-holder><copyright-holder xml:lang="en">Babkina A.V., Khubutiya M.S., Levina O.A., Evseev A.K., Shabanov A.K., Goroncharovskaya I.V., Medvedev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jtransplantologiya.ru/jour/article/view/461">https://www.jtransplantologiya.ru/jour/article/view/461</self-uri><abstract><sec><title>Введение</title><p>Введение. Исследования, посвященные влиянию гипербарической оксигенации, часто представлены модельными экспериментами на животных. В настоящее время растет количество работ, посвященных использованию терапии с помощью гипербарической оксигенации в посттрансплантационном периоде у людей. Актуальность исследования эффективности гипербарической оксигенации в послеоперационном периоде у женщин с опухолями репродуктивной системы после трансплантации органов продиктована временем.</p><p>Цель исследования – оценка эффективности гипербарической оксигенации в комплексной терапии пациенток после трансплантации органов на раннем этапе послеоперационного периода.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Проведен анализ течения раннего послеоперационного периода у 8 женщин с опухолями репродуктивной системы после трансплантации, находившихся на лечении в НИИ СП им. Н.В. Склифосовского, с применением гипербарической оксигенации. Сеансы гипербарической оксигенации проводили в одноместных лечебных барокамерах при режиме 1,2–1,6 АТА в течение 40 минут. Состояние системы окислительно-восстановительного гомеостаза оценивали на основании данных по величине потенциала при разомкнутой цепи платинового электрода в плазме крови, измеренному потенциометрическим методом, и антиоксидантной активности плазмы крови, определенной с помощью циклической вольтамперометрии.</p></sec><sec><title>Результаты</title><p>Результаты. Анализ результатов показал, что имеется прямая связь, свидетельствующая о положительном влиянии гипербарической оксигенации на состояние баланса про- и антиоксидантной систем организма, улучшение показателей крови.</p></sec><sec><title>Вывод</title><p>Вывод. Раннее включение гипербарической оксигенации в комплексное лечение пациенток с опухолями репродуктивной системы после трансплантации органов способствует более быстрому восстановлению баланса про- и антиоксидантной систем организма, показателей крови.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Studies on the effects of hyperbaric oxygenation have often been represented as animal model experiments. Currently, the number of studies on the use of hyperbaric oxygen therapy in the post-transplant period in humans is growing. The need in investigating the efficacy of hyperbaric oxygen therapy in the postoperative period in female transplant patient with tumors of the reproductive system is dictated by time.</p><p>The aim of the study was to evaluate the efficacy of hyperbaric oxygen therapy in the complex treatment of transplant patients at an early stage of the postoperative period.</p></sec><sec><title>Material and methods</title><p>Material and methods. We have studied the course of an early postoperative period in 8 female transplant patients with reproductive system tumors treated in N.V. Sklifosovsky Research Institute for Emergency Medicine, using hyperbaric oxygenation. The hyperbaric oxygen therapy sessions were provided in a single-patient hyperbaric chamber at 1.2–1.6 ATA for 40 minutes. The status of the redox homeostasis system was assessed based on the data of the platinum electrode open circuit potential measured in blood plasma by using the potentiometric method; and the blood plasma antioxidant activity was assessed by cyclic voltammetry.</p></sec><sec><title>Results</title><p>Results. The analysis of the results showed that there was a direct relationship indicating the positive effect of hyperbaric oxygen therapy on the balance status of the pro- and antioxidant systems of the body, and on the improvement of blood counts.</p></sec><sec><title>Conclusion</title><p>Conclusion. The early inclusion of hyperbaric oxygen therapy in the complex treatment of transplant patients with tumors of the reproductive system contributes to a more rapid recovery of pro- and antioxidant systems of the body, blood counts.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация почки</kwd><kwd>опухоли у женщин после трансплантации органов</kwd><kwd>гипербарическая оксигенация</kwd><kwd>потенциал при разомкнутой цепи</kwd><kwd>циклическая вольтамперометрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>kidney transplantation</kwd><kwd>female transplant patient women with tumors of the reproductive system</kwd><kwd>hyperbaric oxygen therapy</kwd><kwd>open circuit potential</kwd><kwd>cyclic voltammetry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Muralidharan V, Christophi C. Hyperbaric oxygen therapy and liver transplantation. 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