transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2020-12-1-28-41transplantologiya-477Research ArticleОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИREVIEW ARTICLES AND LECTURESГипербарическая оксигенация в трансплантологииHyperbaric oxygenation in transplantologyhttps://orcid.org/0000-0002-4811-0845ЛевинаО. А.LevinaO. A.

Ольга Аркадьевна Левина канд. мед. наук, ведущий научный сотрудник отделения неотложной нейрохирургии

Olga A. Levina Cand. Med. Sci., Leading Researcher, Department of Emergency Neurosurgery

https://orcid.org/0000-0002-0832-3272ЕвсеевА. К.EvseevA. K.

Анатолий Константинович Евсеев д-р хим. наук, ведущий научный сотрудник отделения общей реанимации

Anatoly K. Evseev Dr. Chem. Sci., Leading Researcher, Department of the General Intensive Care

https://orcid.org/0000-0002-0746-1884ХубутияМ. Ш.KhubutiyaM. Sh.

Могели Шалвович Хубутия акад. РАН, проф., д-р мед.наук, президент

заведующий кафедрой трансплантологии и искусственных органов 

Mogeli Sh. Khubutiya Acad. of RAS, Prof., Dr. Med. Sci., President

Head of the Department of Transplantology and Artificial Organs

https://orcid.org/0000-0002-5342-8268БабкинаА. В.BabkinaA. V.

Анна Васильевна Бабкина канд. мед. наук, врач-гинеколог отделения экстренной гинекологии

доцент кафедры трансплантологии и искусственных органов 

Anna V. Babkina Cand. Med. Sci., Gynecologist of the Urgent Gynecology Department

Associate Professor of the Department of Transplantology and Artificial Organs

babkina.anya@mail.ruhttps://orcid.org/0000-0002-3417-2682ШабановА. К.ShabanovA. K.

Аслан Курбанович Шабанов д-р мед. наук, старший научный сотрудник отделения общей реанимации

Aslan K. Shabanov Dr. Med. Sci., Senior Resercher, Department of the General Intensive Care

ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»РоссияN.V. Sklifosovsky Research Institute for Emergency MedicineRussian FederationГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»; ФГБОУ ВО МГМСУ им. А.И. Евдокимова МЗ РФРоссияN.V. Sklifosovsky Research Institute for Emergency Medicine; A.I. Yevdokimov Moscow State University of Medicine and DentistryRussian Federation2020180320201212841Copyright © Левина О.А., Евсеев А.К., Хубутия М.Ш., Бабкина А.В., Шабанов А.К., 20202020Левина О.А., Евсеев А.К., Хубутия М.Ш., Бабкина А.В., Шабанов А.К.Levina O.A., Evseev A.K., Khubutiya M.S., Babkina A.V., Shabanov A.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/477

Способность компенсировать любые формы кислородной задолженности при помощи транспортировки кислорода к органам и тканям путем его растворения в жидких средах организма выводит гипербарическую оксигенацию на новый уровень применения в трансплантологии. В обзоре рассмотрены патофизиологические аспекты гипербарической оксигенации при ишемии и реперфузии, особенности использования данного метода в трансплантологии, а также приведены данные по применению гипербарической оксигенации на примере модельных исследований и в клинической практике. Анализ эффективности терапии с помощью гипербарической оксигенации на различных этапах трансплантационного процесса (прекондиционировании, донации, хранении органа, в раннем и позднем посттрансплантационных периодах) позволяет сделать вывод о необходимости большего вовлечения данного метода в трансплантационную практику.

Авторы заявляют об отсутствии конфликта интересов.

The ability to eliminate any form of oxygen debt by transporting oxygen to organs and tissues, by dissolving it in body fluids, brings hyperbaric oxygenation to a new level of application in transplantology. The review discusses the pathophysiological aspects of hyperbaric oxygenation during ischemia and reinfusion, especially when used in transplantology, and also investigations on the use of hyperbaric oxygenation in model experiments and in clinical practice. Analysis of the efficacy of hyperbaric oxygenation therapy at various stages of the transplantation process (preconditioning, donation, organ storage, in the early and late post-transplant periods) allows us to conclude that this method should be more widely involved in transplantation practice.

Authors declare no conflict of interest.

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The authors declare that there are no conflicts of interest present.