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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transplantologiya</journal-id><journal-title-group><journal-title xml:lang="ru">Трансплантология</journal-title><trans-title-group xml:lang="en"><trans-title>Transplantologiya. The Russian Journal of Transplantation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0506</issn><issn pub-type="epub">2542-0909</issn><publisher><publisher-name>IPO Association of Transplantologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23873/2074-0506-2020-12-2-135-142</article-id><article-id custom-type="elpub" pub-id-type="custom">transplantologiya-501</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Новые вызовы инфекционной безопасности при осуществлении медицинской деятельности, связанной с донорством органов и тканей в целях трансплантации</article-title><trans-title-group xml:lang="en"><trans-title>New challenges to infectious safety in the implementation of medical activities related to organ and tissue donation for transplantation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5889-8675</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яремин</surname><given-names>Б. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaremin</surname><given-names>B. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борис Иванович Яремин, канд. мед. наук, доцент, врач-хирург операционного блока трансплантации печени</p></bio><bio xml:lang="en"><p>Boris I. Yaremin, Cand. Med. Sci., Associate Professor, Surgeon of the Operating Suite for Liver Transplantation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2562-902X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назаров</surname><given-names>П. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazarov</surname><given-names>P. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Парвиз Халимович Назаров, заведующий отделением трансплантации органов</p></bio><bio xml:lang="en"><p>Parviz Kh. Nazarov, Head of the Organ Transplantation Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2264-7038</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алекберов</surname><given-names>К. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekberov</surname><given-names>K. F.O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кямран Фаиг Оглы Алекберов, врач-хирург отделения консервирования тканей и производства трансплантатов</p></bio><bio xml:lang="en"><p>Kyamran F.O. Alekberov, Surgeon of the Department for Tissue Preservation and Transplant Production</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6177-8487</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Юрьевич Константинов, канд. мед. наук, доцент, заведующий кафедрой и клиникой инфекционных болезней с эпидемиологией</p></bio><bio xml:lang="en"><p>Dmitriy Yu. Konstantinov, Cand. Med. Sci., Associate Professor, Head of the Department and Clinic of Infectious Diseases with Epidemiology</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2961-202X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудинова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudinova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Владимировна Кудинова, канд. мед. наук, заместитель главного врача по медицинской части</p></bio><bio xml:lang="en"><p>Elena V. Kudinova, Cand. Med. Sci., Deputy Chief Doctor for Medical Attendance</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3009-4744</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Масликова</surname><given-names>У. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maslikova</surname><given-names>U. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульяна Владиславовна Масликова, врач-гематолог </p></bio><bio xml:lang="en"><p>Ulyana V. Maslikova, Hematologist</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6362-7914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новрузбеков</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Novruzbekov</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мурад Сафтарович Новрузбеков, д-р мед. наук, заведующий научным отделением трансплантации печени</p></bio><bio xml:lang="en"><p>Murad S. Novruzbekov, Dr. Med. Sci., Head of the Scientific Department for Liver Transplantation</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГУ «Национальный научный центр трансплантации органов и тканей человека» Министерства здравоохранения и социальной защиты населения Республики Таджикистан</institution><country>Таджикистан</country></aff><aff xml:lang="en"><institution>National Research Center for Transplantation of Human Organs and Tissues</institution><country>Tajikistan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ «Самарская областная клиническая станция переливания крови»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara Regional Clinical Transfusion Station</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ гематологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Center for Hematology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>18</day><month>06</month><year>2020</year></pub-date><volume>12</volume><issue>2</issue><fpage>135</fpage><lpage>142</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яремин Б.И., Назаров П.Х., Алекберов К.Ф., Константинов Д.Ю., Кудинова Е.В., Масликова У.В., Новрузбеков М.С., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Яремин Б.И., Назаров П.Х., Алекберов К.Ф., Константинов Д.Ю., Кудинова Е.В., Масликова У.В., Новрузбеков М.С.</copyright-holder><copyright-holder xml:lang="en">Yaremin B.I., Nazarov P.K., Alekberov K.F., Konstantinov D.Y., Kudinova E.V., Maslikova U.V., Novruzbekov M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jtransplantologiya.ru/jour/article/view/501">https://www.jtransplantologiya.ru/jour/article/view/501</self-uri><abstract><p>Проанализированы изменения в современной научной литературе и регулирующих документах, касающиеся вопросов инфекционной безопасности донорства органов и тканей. Приведены предложения по изменению существующей практики с учетом новых вызовов. Приведены данные об угрозах для безопасности донорства органов и тканей, связанных с пандемией COVID-19.</p></abstract><trans-abstract xml:lang="en"><p>Changes in current scientific literature and regulatory documents related to the issues of infectious safety in organ and tissue donation have been analyzed. The suggestions have been given for changing the existing practices to meet new challenges. Data on threats to the safety of organ and tissue donation associated with the COVID-19 pandemic have been presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>донорство органов</kwd><kwd>инфекционная безопасность</kwd><kwd>передача инфекционных заболеваний</kwd><kwd>ВИЧ</kwd><kwd>гепатит В</kwd><kwd>гепатит С</kwd><kwd>COVID-19</kwd></kwd-group><kwd-group xml:lang="en"><kwd>organ donation</kwd><kwd>infectious safety</kwd><kwd>transmission of infectious diseases</kwd><kwd>HIV</kwd><kwd>hepatitis B</kwd><kwd>hepatitis C</kwd><kwd>COVID-19</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ison MG, Nalesnik MA. An update on donor-derived disease transmission in organ transplantation. Am J Transplant. 2011;11(6):1123–1130. PMID: 21443676http://doi.org/10.1111/j.16006143.2011.03493.x</mixed-citation><mixed-citation xml:lang="en">Ison MG, Nalesnik MA. An update on donor-derived disease transmission in organ transplantation. Am J Transplant. 2011;11(6):1123–1130. PMID: 21443676http://doi.org/10.1111/j.16006143.2011.03493.x</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart DE, Tlusty SM, Taylor KH, Brown RS, Neil HN, Klassen DK, et al. Trends and patterns in reporting of patient safety situations in transplantation. Am J Transplant. 2015;15(12):3123– 3133. PMID: 26560245 http://doi. org/10.1111/ajt.13528</mixed-citation><mixed-citation xml:lang="en">Stewart DE, Tlusty SM, Taylor KH, Brown RS, Neil HN, Klassen DK, et al. Trends and patterns in reporting of patient safety situations in transplantation. Am J Transplant. 2015;15(12):3123– 3133. PMID: 26560245 http://doi. org/10.1111/ajt.13528</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Green M, Covington S, Taranto S, Wolfe C, Bell W, Biggins SW, et al. Donor-derived transmission events in 2013: a report of the organ procurement transplant network ad hoc di sease transmission advisory committee. Transplantation. 2015;99(2):282–287. PMID: 25594557http://doi.org/10.1097/ TP.0000000000000584</mixed-citation><mixed-citation xml:lang="en">Green M, Covington S, Taranto S, Wolfe C, Bell W, Biggins SW, et al. Donor-derived transmission events in 2013: a report of the organ procurement transplant network ad hoc di sease transmission advisory committee. Transplantation. 2015;99(2):282–287. PMID: 25594557http://doi.org/10.1097/ TP.0000000000000584</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Garzoni C, Ison MG. Uniform definitions for donor-derived infectious disease transmissions in solid organ transplantation. Transplantation. 2011;92(12):1297– 1300. PMID: 21996654http://doi. org/10.1097/TP.0b013e318236cd02</mixed-citation><mixed-citation xml:lang="en">Garzoni C, Ison MG. Uniform definitions for donor-derived infectious disease transmissions in solid organ transplantation. Transplantation. 2011;92(12):1297– 1300. PMID: 21996654http://doi. org/10.1097/TP.0b013e318236cd02</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Guide to the quality and safety of organs for transplantation. 6th ed. Strasbourg: European directorate for the quality of medicines &amp; health care; 2016. Available at: https://dondorganes-centre.fr/wp-content/uploads/Guide-ofquality.pdf [Accessed March 31, 2020]</mixed-citation><mixed-citation xml:lang="en">Guide to the quality and safety of organs for transplantation. 6th ed. Strasbourg: European directorate for the quality of medicines &amp; health care;  2016. Available at: https://dondorganes-centre.fr/wp-content/uploads/Guide-ofquality.pdf [Accessed March 31, 2020]</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">SOHO V&amp;S Guidance for competent authorities: Communication and investigation of serious adverse events and reactions associated with human tissues and cells. Vigilance and surveillance of substances of human origins, EU Public health programme. European Commission. 2013. Available at: https://pdfslide. net/documents/soho-vs-guidance-forcompetent-soho-vs-guidance-for-competent-authorities.html [Accessed March 31, 2020]</mixed-citation><mixed-citation xml:lang="en">SOHO V&amp;S Guidance for competent authorities: Communication and investigation of serious adverse events and reactions associated with human tissues and cells. Vigilance and surveillance of substances of human origins, EU Public health programme. European Commission. 2013. Available at: https://pdfslide. net/documents/soho-vs-guidance-forcompetent-soho-vs-guidance-for-competent-authorities.html [Accessed March 31, 2020]</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ison MG, Grossi P, AST Infectious Diseases Community of Practice. Donor derived infections in solid organ transplantation. Am J Transplant. 2013;13(4S): 22–30. PMID: 23464995http://doi. org/10.1111/ajt.12095</mixed-citation><mixed-citation xml:lang="en">Ison MG, Grossi P, AST Infectious Diseases Community of Practice. Donor derived infections in solid organ transplantation. Am J Transplant. 2013;13(4S): 22–30. PMID: 23464995http://doi. org/10.1111/ajt.12095</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Nanni Costa A, Grossi P, Gianelli Castiglione A, Grigioni WF, Italian Transplant Research Network. Quality and safety in the Italian donor evaluation process. Transplantation. 2008;85(8S):S52–S56. PMID: 18425037 http://doi.org/10.1097/ TP.0b013e31816c2f05</mixed-citation><mixed-citation xml:lang="en">Nanni Costa A, Grossi P, Gianelli Castiglione A, Grigioni WF, Italian Transplant Research Network. Quality and safety in the Italian donor evaluation process. Transplantation. 2008;85(8S):S52–S56. PMID: 18425037 http://doi.org/10.1097/ TP.0b013e31816c2f05</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ison MG, Nalesnik MA. An update on donor-derived disease transmission in organ transplantation. Am J Transplant. 2011;11(6):1123–30. PMID: 21443676 http://doi.org/10.1111/j.16006143.2011.03493.x</mixed-citation><mixed-citation xml:lang="en">Ison MG, Nalesnik MA. An update on donor-derived disease transmission in organ transplantation. Am J Transplant. 2011;11(6):1123–30. PMID: 21443676 http://doi.org/10.1111/j.16006143.2011.03493.x</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Хубутия М.Ш., Солонин С.А., Баженов А.И., Кобзева Е.Н., Смирнова Ю.В., Годков М.А. Риски передачи гемоконтактных вирусных инфекций при гемотрансфузиях, трансплантации органов и тканей. Трансплантология. 2015;(4):23–33.</mixed-citation><mixed-citation xml:lang="en">Khubutiya MSh, Solonin SA, Bazhenov AI, Kobzeva EN, Smirnova YuV, Godkov MA. Risks of transmission blood-borne viral infections via blood transfusion, organ and tissue transplantation. Transplantologiya. The Russian Journal of Transplantation. 2015;(4):23–33. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Журавель С.В., Кузнецова Н.К., Черненькая Т.В., Уткина И.И. Передача инфекционных возбудителей от органов донора реципиенту. Нужны ли изменения в оценке рисков? Трансплантология. 2015;(1):7–12.</mixed-citation><mixed-citation xml:lang="en">Zhuravel SV, Kuznetsova NK, Chernenkaya TV, Utkina II. Transmission of infectious agents from the donor to the recipient. Do we need change in the risk assessment?  Transplantologiya. The Russian Journal of Transplantation. 2015;(1):7–12. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Хубутия М.Ш., Солонин С.А., Кобзева Е.Н., Годков М.А. Гемоконтактные вирусные инфекции у доноров крови, потенциальных доноров органов и тканей. Трансплантология. 2016;(2):45–57.</mixed-citation><mixed-citation xml:lang="en">Khubutiya MSh, Solonin SA, Kobzeva EN, Godkov MA. Blood-borne viral infections among blood, organ and tissue donors. Transplantologiya. The Russian Journal of Transplantation. 2016;(2):45– 57. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Хубутия М.Ш., Солонин С.А., Годков М.А. Трансплантация органов от доноров, зараженных гемоконтактными вирусными инфекциями. Опыт зарубежных стран. Трансплантология. 2016;(4):48–57.</mixed-citation><mixed-citation xml:lang="en">Khubutiya MSh, Solonin SA, Godkov MA. Transplantation of organs from donors infected with bloodborne viral infections. The experience of foreign countries. Transplantologiya. The Russian Journal of Transplantation. 2016;(4):48–57. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Michaels MG, La Hoz RM, DanzigerIsakov L, Blumberg EA, Kumar D, Green M, et al. Coronavirus disease 2019: Implications of emerging infections for transplantation. Am J Transplant. 2020 Feb 24. PMID: 32090448 http://doi. org/10.1111/ajt.15832 [Online ahead of print]</mixed-citation><mixed-citation xml:lang="en">Michaels MG, La Hoz RM, DanzigerIsakov L, Blumberg EA, Kumar D, Green M, et al. Coronavirus disease 2019: Implications of emerging infections for transplantation. Am J Transplant. 2020 Feb 24. PMID: 32090448 http://doi. org/10.1111/ajt.15832 [Online ahead of print]</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kumar D, Tellier R, Draker R, Levy G, Humar A. Severe Acute Respiratory Syndrome (SARS) in a liver transplant recipient and guidelines for donor SARS screening. Am J Transplant. 2003;3(8):977–981. PMID: 12859532 https://doi.org/10.1034/j.16006143.2003.00197.x</mixed-citation><mixed-citation xml:lang="en">Kumar D, Tellier R, Draker R, Levy G, Humar A. Severe Acute Respiratory Syndrome (SARS) in a liver transplant recipient and guidelines for donor SARS screening. Am J Transplant. 2003;3(8):977–981. PMID: 12859532 https://doi.org/10.1034/j.16006143.2003.00197.x</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">D'Antiga L. Coronaviruses and immunosuppressed patients. The facts during the third epidemic. Liver Transplantation. 2020; March 20. https://doi. org/10.1002/lt.25756 [Online ahead of print]</mixed-citation><mixed-citation xml:lang="en">D'Antiga L. Coronaviruses and immunosuppressed patients. The facts during the third epidemic. Liver Transplantation. 2020; March 20. https://doi. org/10.1002/lt.25756 [Online ahead of print]</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Martín-Delgado MC, MartínezSoba F, Masnou N, Pérez-Villares JM, Pont T, Sánchez Carretero MJ, et al. Summary of Spanish recommendations on intensive care to facilitate organ donation. Am J Transplant. 2019;19:1782– 1791. https://doi.org/10.1111/ajt.15253</mixed-citation><mixed-citation xml:lang="en">Martín-Delgado MC, MartínezSoba F, Masnou N, Pérez-Villares JM, Pont T, Sánchez Carretero MJ, et al. Summary of Spanish recommendations on intensive care to facilitate organ donation. Am J Transplant. 2019;19:1782– 1791. https://doi.org/10.1111/ajt.15253</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
