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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">transplantologiya</journal-id><journal-title-group><journal-title xml:lang="ru">Трансплантология</journal-title><trans-title-group xml:lang="en"><trans-title>Transplantologiya. The Russian Journal of Transplantation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0506</issn><issn pub-type="epub">2542-0909</issn><publisher><publisher-name>IPO Association of Transplantologists</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23873/2074-0506-2020-12-3-220-230</article-id><article-id custom-type="elpub" pub-id-type="custom">transplantologiya-517</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Предикторы эффективности применения экстракорпоральной мембранной оксигенации при острой дыхательной недостаточности</article-title><trans-title-group xml:lang="en"><trans-title>Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8511-9646</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Брыгин</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Brygin</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павел Александрович Брыгин, канд. мед. наук, заведующий отделением реанимации для ожоговых больных</p><p>129090, Москва, Большая Сухаревская площадь, д. 3</p></bio><bio xml:lang="en"><p>Pavel A. Brygin, Cand. Med. Sci., Head of the Intensive and Critical Care Unit for Burn Patients </p><p>3 Bolshaya Sukharevskaya Sq., Moscow 129090</p></bio><email xlink:type="simple">p.brygin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9992-9260</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавель</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravel</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Владимирович Журавель, д-р мед. наук, заведующий научным отделением анестезиологии, реаниматологии и интенсивной терапии </p><p>129090, Москва, Большая Сухаревская площадь, д. 3</p></bio><bio xml:lang="en"><p>Sergey V. Zhuravel, Dr. Med. Sci., Head of the Scientific Department for Anesthesiology, Intensive and Critical Care </p><p>3 Bolshaya Sukharevskaya Sq., Moscow 129090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1181-518X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Троицкий</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troitskiy</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> врач-ординатор отделения анестезиологии, реаниматологии и интенсивной терапии</p><p>129090, Москва, Большая Сухаревская площадь, д. 3</p></bio><bio xml:lang="en"><p>Daniil A. Troitskiy, Resident Physician of the Department for Anesthesiology, Intensive and Critical Care </p><p>3 Bolshaya Sukharevskaya Sq., Moscow 129090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5685-4916</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Уткина</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Utkina</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p> канд. мед. наук, старший научный сотрудник отделения анестезиологии, реаниматологии и интенсивной терапии</p><p>129090, Москва, Большая Сухаревская площадь, д. 3</p></bio><bio xml:lang="en"><p>Irina I. Utkina, Cand. Med. Sci., Senior Researcher, Department for Anesthesiology, Intensive and Critical Care </p><p>3 Bolshaya Sukharevskaya Sq., Moscow 129090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Research Institute for Emergency Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>10</day><month>09</month><year>2020</year></pub-date><volume>12</volume><issue>3</issue><fpage>220</fpage><lpage>230</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Брыгин П.А., Журавель С.В., Троицкий Д.А., Уткина И.И., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Брыгин П.А., Журавель С.В., Троицкий Д.А., Уткина И.И.</copyright-holder><copyright-holder xml:lang="en">Brygin P.A., Zhuravel S.V., Troitskiy D.A., Utkina I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.jtransplantologiya.ru/jour/article/view/517">https://www.jtransplantologiya.ru/jour/article/view/517</self-uri><abstract><p>В статье обсуждается проблема прогнозирования возможности восстановления функции легких при остром респираторном дистресс-синдроме при проведении экстракорпоральной мембранной оксигенации. Рассмотрены данные международных исследований СESAR и EOLIA, посвященных анализу исходов экстракорпоральной мембранной оксигенации при остром респираторном дистресс-синдроме. Обсуждается противоречивость полученных результатов. Приведены прогностические шкалы PRESERVE и PESP, разработанные на основании результатов этих исследований, обсуждается ограниченность применимости их при различных вариантах острого респираторного дистресс-синдрома. Мы предлагаем разделить предикторы исхода применения экстракорпоральной мембранной оксигенации при остром респираторном дистресс-синдроме на 4 группы: 1. Критерии тяжести поражения легких, включающие параметры кислородотранспортной функции легких и показатели механических свойств легких. 2. Время развития острой дыхательной недостаточности и начала экстракорпоральной мембранной оксигенации, отражающие как скорость развития патологических процессов в легких, так и оптимальность принятия решения о начале экстракорпоральной мембранной оксигенации. 3. Этиология легочных нарушений, напрямую влияющая на обратимость патологических процессов в легких. 4. Тяжесть общего состояния больного, включающая выраженность проявлений полиорганной недостаточности, степень декомпенсации сопутствующих хронических заболеваний, в том числе – онокологических и связанных с иммуносупрессией. Определенные заболевания сопровождаются повышенным риском специфических осложнений, связанных с проведением процедуры экстракорпоральной мембранной оксигенации, в частности – геморрагических.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of this article is to describe the problem of predicting the lung function recovery in patients with extracorporeal membrane oxygenation for acute respiratory distress syndrome. Data from CESAR and EOLIA clinical trials on the efficacy of extracorporeal membrane oxygenation in patients with acute respiratory distress syndrome have been reviewed and some controversial results discussed. The prognostic PRESERVE and RESP scores developed as prognostic tools on the basis of the results of these studies, are presented, the limitations of their applicability in various forms of acute respiratory distress syndrome are discussed. We propose to subdivide the predictors of the extracorporeal membrane oxygenation outcome in patients with acute respiratory distress syndrome into 4 following groups: 1. Lung injury severity criteria, including parameters of their lung mechanical and functional properties. 2. Time from acute respiratory failure onset to extracorporeal membrane oxygenation initiation, which reflects the rate of pathological processes in lungs and timing of decision to initiate extracorporeal membrane oxygenation. 3. The etiology of pulmonary disorders, directly affecting the reversibility of pathological processes in the lungs. 4. The severity of the patient's general condition, including the severity of manifestations of multiple organ failure, the degree of decompensation of concomitant chronic diseases, including oncological and associated with immunosuppression. Several diseases are associated with a higher risk of specific complications, particularly hemorrhagic, during extracorporeal membrane oxygenation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>экстракорпоральная мембранная оксигенация</kwd><kwd>острый респираторный дистресс-синдром</kwd><kwd>острая дыхательная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>extracorporeal membrane oxygenation</kwd><kwd>acute respiratory distress syndrome</kwd><kwd>acute respiratory failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Evseev AK, Zhuravel SV, Alentiev AYu, Goroncharovskaya IV, Petrikov SS. 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