transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2022-14-4-476-487transplantologiya-709Research ArticleОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИREVIEW ARTICLES AND LECTURESРазвитие онкологических заболеваний после трансплантации органовDevelopment of oncological diseases after organ transplantationhttps://orcid.org/0000-0002-5342-8268БабкинаА. В.BabkinaA. V.

Анна Васильевна Бабкина, доц., канд. мед. наук, врач отделения острых гинекологических заболеваний; доцент кафедры

129090, Москва, Большая Сухаревская пл., д. 3

Anna V. Babkina, Assoc. Prof., Cand. Sci. (Med.), Gynecologist of the Urgent Gynecology Department; Associate Professor 

3 Bolshaya Sukharevskaya Sq., Moscow 129090

20 Bldg. 1 Delegatskaya St., Moscow 127473

BabkinaAV@sklif.mos.ruhttps://orcid.org/0000-0002-0746-1884ХубутияМ. Ш.KhubutiyaM. Sh.

Могели Шалвович Хубутия, акад. РАН, проф., д-р мед. наук, президент; заведующий кафедрой

129090, Москва, Большая Сухаревская пл., д. 3

127473, Москва, Делегатская ул., д. 20, стр. 1

Mogeli Sh. Khubutiya, Academician of the Russian Academy of Sciences, Prof., Dr. Sci. (Med.), President; Head of the Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090

20 Bldg. 1 Delegatskaya St., Moscow 127473

KhubutiyaMS@sklif.mos.ruГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»; Кафедра трансплантологии и искусственных органов ФГБОУ ВО МГМСУ им. А.И. Евдокимова МЗ РФРоссияN.V. Sklifosovsky Research Institute for Emergency Medicine; Department of Transplantology and Artificial Organs, A.I. Yevdokimov Moscow State University of Medicine and DentistryRussian Federation202221122022144476487Copyright © Бабкина А.В., Хубутия М.Ш., 20222022Бабкина А.В., Хубутия М.Ш.Babkina A.V., Khubutiya M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/709

С увеличением популяции пациентов с трансплантированными органами пропорционально высоким стал риск развития онкологических заболеваний, которые становятся причиной не только низкого качества жизни, но и причиной высокой смертности пациентов с пересаженными органами. В обзоре рассмотрены факторы риска, частота и влияние на выживаемость злокачественных новообразований у пациентов с пересаженными органами. Быстрое развитие клинической трансплантологии, использование новых препаратов и схем иммуносупрессии ставят новые задачи перед онкологами и трансплантологами. Анализ частоты онкологической патологии у пациентов с пересаженными органами позволяет сделать вывод о ее влиянии на отдаленный жизненный прогноз и необходимости включения превентивных мер в трансплантационную практику.

With the increase in the population of patients with transplanted organs, the risk of developing oncological diseases has become proportionally high, which may be the cause of poor quality of life, and also of a high mortality among the patients with transplanted organs. The review examines the risk factors, incidence, and the impact of malignant neoplasms on the survival in patients with transplanted organs. The rapid development of clinical transplantology, the use of new drugs and immunosuppression regimens poses new challenges for oncologists and transplantologists. The analysis of oncopathology incidence in patients with transplanted organs allows us to conclude about its impact on the long-term life prognosis and the need to include preventive measures in transplantation practice.

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The authors declare that there are no conflicts of interest present.