transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2023-15-1-46-60transplantologiya-744Research ArticleКЛИНИЧЕСКИЕ НАБЛЮДЕНИЯCASE REPORTSГигантская постинфарктная аневризма задней стенки левого желудочка, осложненная митральной недостаточностьюGiant postinfarction posterolateral left ventricular aneurysm, complicated by mitral insufficiencyhttps://orcid.org/0000-0002-3037-3292БикбоваН. М.BikbovaN. M.

Наталья Марсовна Бикбова - врач ультразвуковой диагностики, научный сотрудник отделения  неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Natalya M. Bikbova - Diagnostic Ultrasonography Physician, Researcher of the Emergency Cardiac Surgery Department

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

BikbovaNM@sklif.mos.ruhttps://orcid.org/0000-0003-4145-1337МазановМ. Х.MazanovM. Kh.

Мурат Хамидбиевич Мазанов - канд. мед. наук, врач-сердечно-сосудистый хирург, старший научный сотрудник отделения неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Murat Kh. Mazanov - Cand. Sci. (Med.), Cardiovascular Surgeon, Senior Researcher of the Emergency Cardiac Surgery Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

MazanovMH@sklif.mos.ruhttps://orcid.org/0000-0002-2971-9188СагировМ. А.SagirovM. A.

Марат Анварович Сагиров - канд. мед. наук, врач-сердечно-сосудистый хирург, заведующий 1-м кардиохирургическим отделением 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Marat A. Sagirov - Cand. Sci. (Med.), Cardiovascular Surgeon, Head of the 1st Cardiac Surgery Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

SagirovMA@sklif.mos.ruhttps://orcid.org/0000-0002-2249-8925ХаритоноваН. И.KharitonovaN. I.

Надежда Ивановна Харитонова - врач ультразвуковой диагностики, старший научный сотрудник отделения неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Nadezhda I. Kharitonova - Diagnostic Ultrasonography Physician, Senior Researcher of the Emergency Cardiac Surgery Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

KharitonovaNI@sklif.mos.ruhttps://orcid.org/0000-0002-0760-0995БарановА. А.BaranovA. A.

Андрей Андреевич Баранов - врач-сердечно-сосудистый хирург, младший научный сотрудник отделения неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Andrey A. Baranov - Cardiovascular Surgeon, Junior Researcher of the Emergency Cardiac Surgery Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

BaranovAA@sklif.mos.ruhttps://orcid.org/0000-0003-4078-5263АргирИ. А.ArgirI. A.

Иван Александрович Аргир, врач-сердечно-сосудистый хирург, младший научный сотрудник отделения неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Ivan A. Argir - Cardiovascular Surgeon, Junior Researcher of the Emergency Cardiac Surgery Department 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

ArgirIA@sklif.mos.ruhttps://orcid.org/0000-0002-2379-9631МингалимоваА. Р.MingalimovaI. R.

Альфия Рависовна Мингалимова - врач-кардиолог 1-го кардиохирургического отделения; аспирант 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

101990, Россия, Москва, Петроверигский пер., д. 10, стр. 3

lfiya R. Mingalimova - Cardiologist of the 1st Cardiac Surgery Department; Postgraduate Student

 3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

 10 Bldg. 3 Petroverigsky Ln., Moscow 101990 Russia 

MingalimovaAR@sklif.mos.ruhttps://orcid.org/0000-0003-3283-0562КамбаровС. Ю.KambarovS. Yu.

Сергей Юрьевич Камбаров - д-р мед. наук, врач-сердечно-сосудистый хирург, заведующий отделением неотложной кардиохирургии 

 129090, Россия, Москва, Большая Сухаревская пл., д. 3 

Sergey Yu. Kambarov - Dr. Sci. (Med.), Cardiovascular Surgeon, Head of the Emergency Cardiac Surgery Department 

 3 Bolshaya Sukharevskaya Sq., Moscow 129090 Russia 

KambarovSY@sklif.mos.ruГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»РоссияN.V. Sklifosovsky Research Institute for Emergency MedicineRussian FederationГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»; ФГБУ «Национальный медицинский исследовательский центр терапии и профилактической медицины» МЗ РФРоссияN.V. Sklifosovsky Research Institute for Emergency Medicine; National Medical Research Center for Therapy and Preventive Medicine Russian Federation2023180320231514660Copyright © Бикбова Н.М., Мазанов М.Х., Сагиров М.А., Харитонова Н.И., Баранов А.А., Аргир И.А., Мингалимова А.Р., Камбаров С.Ю., 20232023Бикбова Н.М., Мазанов М.Х., Сагиров М.А., Харитонова Н.И., Баранов А.А., Аргир И.А., Мингалимова А.Р., Камбаров С.Ю.Bikbova N.M., Mazanov M.K., Sagirov M.A., Kharitonova N.I., Baranov A.A., Argir I.A., Mingalimova I.R., Kambarov S.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/744

Ишемическая болезнь сердца занимает лидирующее место в структуре сердечно-сосудистых заболеваний. Ранняя реперфузионная терапия при остром инфаркте миокарда привела к снижению смертности и тяжелых осложнений ишемической болезни сердца. Несмотря на достижения в лечении ишемической болезни сердца, дилатация и ремоделирование левого желудочка развиваются у 20% пациентов, перенесших инфаркт, приводя к митральной недостаточности и систолической дисфункции левого желудочка.Аневризма левого желудочка является отсроченным тяжелейшим осложнением инфаркта миокарда, значительно ухудшающим прогноз. Большие аневризмы левого желудочка выступают причиной прогрессирующей дилатации левого желудочка, его объемной перегрузки с повышением напряжения стенок в участках без инфаркта, снижения функциональных показателей левого желудочка, тромбообразования в полости аневризмы, жизнеугрожающих нарушений ритма и внезапной смерти.Постинфарктное ремоделирование левого желудочка может приводить к вторичной митральной регургитации, которая является независимым предиктором смертности в отдаленном периоде.Хирургическое лечение ишемической болезни сердца и ее осложнений – одна из главных проблем современной сердечно-сосудистой хирургии.

Ischemic heart disease holds the leading position in the structure of cardiovascular diseases. Early reperfusion therapy for acute myocardial infarction led to a decrease in mortality and severe complications of coronary artery disease. Despite advances in the treatment of coronary artery disease, dilatation and remodeling of the left ventricle develop in 20% of patients who have had a heart attack, leading to mitral insufficiency and systolic dysfunction of the left ventricle. Aneurysm of the left ventricle is a delayed severe complication of myocardial infarction, which significantly worsens the prognosis. Large aneurysms of the left ventricle cause progressive dilatation of the left ventricle, its volumetric overload with an increase in wall tension in the non-infarction zone, decreased functional characteristics of the left ventricle, thrombosis in the aneurysm cavity, life-threatening arrhythmias, and sudden death. Postinfarction left ventricular remodeling can lead to secondary mitral regurgitation, which is an independent predictor of mortality in the longterm period. Surgical treatment of coronary heart disease and its complications is one of the main problems of modern cardiovascular surgery.

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The authors declare that there are no conflicts of interest present.