transplantologiyaТрансплантологияTransplantologiya. The Russian Journal of Transplantation2074-05062542-0909IPO Association of Transplantologists10.23873/2074-0506-2023-15-1-98-117transplantologiya-749Research ArticleОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИREVIEW ARTICLES AND LECTURESЛегко сказать, трудно сделать. К юбилею двух фундаментальных открытий. Часть 3Easy to say, hard to do. To the anniversary of two fundamental discoveries. Part 3https://orcid.org/0000-0003-4156-434XАнисимовА. Ю.AnisimovA. Yu.

Андрей Юрьевич Анисимов, проф., д-р мед. наук, заведующий кафедрой неотложной медицинской помощи и симуляционной медицины 

 420008, Россия, Казань, Кремлевская ул., д. 18 

Andrey Yu. Anisimov - Prof., Dr. Sci. (Med.), Head of the Department of Emergency Medical Care and Simulation Medicine

aanisimovbsmp@yandex.ruФГАОУ ВО «Казанский (Приволжский) федеральный университет»РоссияInstitute of Fundamental Medicine and Biology of Kazan (Volga Region) Federal UniversityRussian Federation20232003202315198117Copyright © Анисимов А.Ю., 20232023Анисимов А.Ю.Anisimov A.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.jtransplantologiya.ru/jour/article/view/749

В преддверии юбилейных дат двух исторических событий: 145-летия со дня экспериментального выполнения фистулы Экка и 55-летия со дня успешной клинической апробации операции селективного дистального спленоренального анастомоза, – проведен ретроспективный анализ ключевых исторических этапов развития хирургии портальной гипертензии от первых попыток описания анатомии сосудистой системы печени, объяснения ее предназначения в организме, разработки прямого портокавального соустья, широкого применения селективных спленоренальных анастомозов, до методики Transjugular Intrahepatic Portosystemic Shunt и ортотопической трансплантации печени. При этом внимание сосредоточено на наиболее ярких персонажах исследователей и клиницистов, которые прошли этот путь. Обоснована целесообразность комплексного подхода в решении проблем портальной гипертензии с развитием как фундаментальных, так и прикладных клинических и организационных аспектов. Показано, что открытия, рожденные при обобщении результатов, достигнутых многочисленными исследователями, способствовали лучшему пониманию этой области медицины и стали прочным фундаментом того, что мы имеем сегодня, являясь надежной площадкой для успешного старта в будущее.

On the eve of the anniversaries of two historical events: the 145th anniversary of the experiments in which Eck's fistula was performed and the 55th anniversary of the successful clinical approbation of the selective distal splenorenal anastomosis, a retrospective analysis of the key historical stages in the development of portal hypertension surgery was performed: from the first attempts to describe the anatomy of the hepatic vascular system, explaining its purpose in the body, the development of direct portacaval anastomosis, and the widespread use of selective splenorenal anastomoses, to the Transjugular Intrahepatic Portosystemic Shunt procedure and orthotopic liver transplantation. Meantime, the emphasis has been focused on the most colorful characters of researchers and clinicians who passed this path. The expediency of an integrated approach in solving the problems of portal hypertension with the development of both fundamental and applied clinical and organizational aspects has been substantiated. It is shown that the discoveries born from summarizing the results achieved by numerous researchers have contributed to a better understanding of this field of medicine, have become a solid foundation for what we have today and are a reliable platform for a successful start into the future.

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The authors declare that there are no conflicts of interest present.