References

transplantologiya

Трансплантология

Transplantologiya. The Russian Journal of Transplantation

2074-05062542-0909

IPO Association of Transplantologists

transplantologiya-89

Research Article

ОБЗОРНЫЕ СТАТЬИ И ЛЕКЦИИ

REVIEW ARTICLES AND LECTURES

ВЕДЕНИЕ ПОТЕНЦИАЛЬНОГО ДОНОРА СО СМЕРТЬЮ МОЗГА (ЧАСТЬ 1)

Management of a potential donor with brain death (PART 1)

Виноградов

В. Л.

Vinogradov

V. L.

v.l.vinogradov@gmail.com

ГБУЗ «НИИ скорой помощи им. Н.В. Склифосовского ДЗМ»РоссияN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentRussian Federation

2014

04022016

032331

2016

Виноградов В.Л.

Vinogradov V.L.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.jtransplantologiya.ru/jour/article/view/89

Основным фактором, ограничивающим трансплантацию, является недостаток донорских органов. В настоящее время большинство трансплантаций производится от доноров со смертью мозга (СМ). Со смертью в большинстве случаев связана выраженная физиологическая нестабильность, которая может привести или к ухудшению функции донорского органа до эксцизии, или к потере донора. При активном или даже агрессивном ведении донора возможны управление и коррекция патофизиологических процессов в донорских органах, тем самым увеличивается число и улучшается функциональное состояние донорских органов.

Агрессивная стратегия ведения потенциальных доноров со СМ требует изменения не только в подходах к интенсивной терапии, но и философии в оценке проводимой работы. Несмотря на разработку и внедрение различных протоколов ведения доноров со СМ, оптимального сочетания целей, мониторинга, специфической терапии до настоящего момента пока не достигнуто.

The lack of donor organs is the main factor limiting organ transplantation. Currently, the majority of transplants are taken from brain-dead donors. In most cases the brain death is associateed with a severe physiologic instability that may deteriorate the donor organ function prior to the excision or lead to the loss of the donor. An active or even aggressive management of a donor allows the control and correction of pathophysiological processes in donor organs, thus increasing the number and improving the functional condition of donor organs.

An aggressive management strategy for a potential donor with brain death requires to change both the approach to intensive care, and the philosophic aspect in the evaluation of this work. Despite the development and implementation of various protocols for brain-dead donors, an optimum combination of objectives, monitoring, specific therapy has not been worked out yet.

донор со смертью мозгаведение донора со смертью мозгатрансплантацияинтенсивная терапия

brain-dead donormanagement of a brain-dead donortransplantationintensive care.

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The authors declare that there are no conflicts of interest present.