PHENOMENON OF DEMIKHOV. In the Sklifosovsky Institute (1960–1986). Demichow W. Die experimentelle Transplantation lebenswichtiger Organe. Berlin: VEB Verlag Volk und Gesundheit, 1963
https://doi.org/10.23873/2074-0506-2020-12-1-61-75
Abstract
The article has discussed V.P. Demikhov's views on a homoplastic transplantation of tissues and organs in 1963 and his achievements in experimental transplantation by that time. The authors first translated the monograph Die experimentelle Transplantation lebenswichtiger Organe (1963) from German into Russian and presented V.P. Demikhov's Preface to it. In this text, having critically analyzed the current provisions in the field of immunobiology, V.P. Demikhov came to the conclusion that a number of his achievements contradicted those provisions and did not fit into the framework of existing immunobiological laws. In 1963, confessing the primacy of function over structure, V.P. Demikhov believed that the restoration of blood circulation in transplanted organs played the main role in their survival, and the subsequent functioning of the transplanted organ for a long time meant its engraftment. In this text V.P. Demikhov for the first time substantiated the model of a “physiological organism” he had invented for reviving a human in a state of agony, for creating a bank of organs, growing it in infants and rejuvenating the elderly.
Authors declare no conflict of interest.
Keywords
history of transplantology,
V.P. Demikhov,
W. Demichow,
Die experimentelle Transplantation lebenswichtiger Organe,
1963
Supporting agencies: The study was performed without external funding.
About the Authors
S. P. Glyantsev
A.N. Bakoulev National Medical Research Center for Cardiovascular Surgery;
N.A. Semashko National Research Institute of Public Health
Russian Federation
Russian Federation
Sergey P. Glyantsev Prof., Dr. Med. Sci., Head of the Department of the History of Cardiovascular Surgery
Head of the Medical History Unit within the Medical History Department
A. Werner
Cardiothoracic Surgery Clinic, HELIOS Hospital Krefeld
Germany
Artur Werner Dr. Med., Resident Doctor
Germany
Artur Werner Dr. Med., Resident Doctor
References
1. Glyantsev SP. Phenomenon of Demikhov. In the Sklifosovsky Institute (1960– 1986). Research Coordination Council of the USSR Healthcare Ministry: Missed opportunities. Part 1 (1963). Transplantologiya. The Russian Journal of Transplantation. 2019;11(3):244–258. (In Russ.). https://doi.org/10.23873/2074-0506- 2019-11-3-244-258
2. Glyantsev SP. Phenomenon of Demikhov. In the Sklifosovsky Institute (1960– 1986). Research Coordination Council of the USSR Healthcare Ministry: Missed opportunities. Part 2 (1963). Transplantologiya. The Russian Journal of Transplantation. 2019;11(4):330–348. (In Russ.). https://doi.org/10.23873/2074-0506- 2019-11-4-330-348
3. Demikhov VP. Peresadka organov: eto vozmozhno? Moscow: Znaniye Publ.; 1959. (In Russ.).
4. Demikhov VP. Peresadka zhiznenno vazhnykh organov v eksperimente (opyty po peresadke serdtsa, legkikh, golovy, pochek i drugikh organov). Moscow: Medgiz Publ.; 1960. (In Russ.).
5. Demikhov VP. Experimental Transplantation of Vital Organs. New-York: Consultants Bureau Enterprises; 1962.
6. Demichow W. Die experimentelle Transplantation lebenswichtiger Organe. Berlin: VEB Verlag Volk und Gesundheit; 1963.
7. Demikhov VP. Ob oshibochnosti «zakona serdtsa» Starlinga. Bulletin of Experimental Biology and Medicine. 1950;29(5):397–399. (In Russ.).
8. Glyantsev SP. Phenomenon of Demikhov. "Experimental Transplantation of Vital Organs" (1960). Myocardial revascularization, experimental physiology of blood circulation. Transplantologiya. The Russian Journal of Transplantation. 2018;10(1):57–67. (In Russ.). https://doi. org/10.23873/2074-0506-2018-10-1-57- 67
Review
For citations:
Glyantsev S.P., Werner A. PHENOMENON OF DEMIKHOV. In the Sklifosovsky Institute (1960–1986). Demichow W. Die experimentelle Transplantation lebenswichtiger Organe. Berlin: VEB Verlag Volk und Gesundheit, 1963. Transplantologiya. The Russian Journal of Transplantation. 2020;12(1):61-75. https://doi.org/10.23873/2074-0506-2020-12-1-61-75
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