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Transplantologiya. The Russian Journal of Transplantation

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Phenomenon of Demikhov. At N.V. Sklifosovsky Institute (1960–1986). V.P. Demikhov and his experiments in the field of organ transplantation in 1971–1972

https://doi.org/10.23873/2074-0506-2023-15-2-279-294

Abstract

Having reviewed the archival documents, we enlightened the results of research performed by V.P. Demikhov and the employees of the Organ Transplantation Laboratory at the N.V. Sklifosovsky Research Institute, as well as V.P. Demikhov’s life and work in 1971–1972. During those years he continued to conduct the research required, as he believed, for practical healthcare. In 1971, together with M.M. Razgulov, he proposed a method for connecting blood vessels, a method for transplanting an upper limb together with a scapula, repeated experiments previously carried out on dogs, on human corpses (revitalization of a cadaveric heart, monitoring its activity using electrocardiography, implanting an additional heart into the cadaver’s chest in order to implement the technique in clinic for the treatment of heart failure), presented the results of his research at the X International Congress on Cardiovascular Diseases. We have also shown that in 1971–1972 V.P. Demikhov performed 76 experimental interventions, most of which were aimed at the development of a technique for transplanting an isolated cardiopulmonary complex and heart, as well as the technique for their revitalization. It should be noted that all the methods of organ transplantation developed by him were intended for implementation in clinic. However, no method was introduced into clinic during his lifetime. The fact is that the studies of V.P. Demikhov in the field of organ transplantation could not be adequately supplied from the material, technical and economic point, since they did not correspond to the main trends of the scientific and practical activities of the N.V. Sklifosovsky Institute – to improve the organizing system of rendering an emergency and urgent care to the population of Moscow in acute diseases and injuries.

About the Authors

S. P. Glyantsev
A.N. Bakulev National Medical Research Center for Cardiovascular Surgery; N.A. Semashko National Research Institute of Public Health
Russian Federation

Sergey P. Glyantsev, Prof., Dr. Sci. (Med.), Head of the Department of the History of Cardiovascular Surgery; Head of the Sector for the History of Medicine and Factography of the Department for the History of Medicine, 
80%, concept development, search for sources, their analysis, generalization, text writing 

135 Roublyevskoe Hwy., Moscow 121552;
12 Bldg. 1 Vorontsovo Pole St., Moscow 105064;



Yu. A. Shabunts
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Yuriy A. Shabunts, 5th year student, Institute of Clinical Medicine, 
20%, copying the data from the sources according to the study design, their primary analysis 

8 Bldg. 2 Trubetskaya St., Moscow 119991



References

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Review

For citations:


Glyantsev S.P., Shabunts Yu.A. Phenomenon of Demikhov. At N.V. Sklifosovsky Institute (1960–1986). V.P. Demikhov and his experiments in the field of organ transplantation in 1971–1972. Transplantologiya. The Russian Journal of Transplantation. 2023;15(2):279-294. https://doi.org/10.23873/2074-0506-2023-15-2-279-294

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ISSN 2074-0506 (Print)
ISSN 2542-0909 (Online)