Rare cases of primarily infected kidney graft transplantation with the development of purulent complications
https://doi.org/10.23873/2074-0506-2024-16-3-353-363
Abstract
Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis.
Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients.
Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes.
Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life.
About the Authors
N. V. ShmarinaRussian Federation
Nonna V. Shmarina, Cand. Sci. (Med.), Surgeon, Senior Researcher, Department of Kidney and Pancreas Transplantation; Associate Professor
3 Bolshaya Sukharevskaya Sq., Moscow 129090
1 Ostrovityanov St., Moscow 117997
K. E. Lazareva
Russian Federation
Kseniya E. Lazareva, Cand. Sci. (Med.), Endocrinologist, Research Associate, Department of Kidney and Pancreas Transplantation; Associate Professor
3 Bolshaya Sukharevskaya Sq., Moscow 129090
4 Dolgorukovskaya St., Moscow 127006
I. V. Dmitriev
Russian Federation
Ilya V. Dmitriev, Dr. Sci. (Med.), Head of the Department of Kidney and Pancreas Transplantation; Associate Professor
3 Bolshaya Sukharevskaya Sq., Moscow 129090
1 Ostrovityanov St., Moscow 117997
A. G. Balkarov
Russian Federation
Aslan G. Balkarov, Cand. Sci. (Med.), Head of the Scientific Department of Kidney and Pancreas Transplantation; Associate Professor; Head of the Organizational and Methodological Department for Transplantology
3 Bolshaya Sukharevskaya Sq., Moscow 129090
1 Ostrovityanov St., Moscow 117997
30 Bolshaya Tatarskaya St., Moscow 115184
D. V. Lonshakov
Russian Federation
Denis V. Lonshakov, Surgeon, Department of Kidney and Pancreas Transplantation
3 Bolshaya Sukharevskaya Sq., Moscow 129090
N. S. Zhuravel
Russian Federation
Nikita S. Zhuravel, Cand. Sci. (Med.), Surgeon, Junior Researcher, Department of Kidney and Pancreas Transplantation; Assistant
3 Bolshaya Sukharevskaya Sq., Moscow 129090
4 Dolgorukovskaya St., Moscow 127006
V. V. Smirnova
Russian Federation
Viktoriya V. Smirnova, Surgeon, Junior Researcher, Department of Kidney and Pancreas Transplantation
3 Bolshaya Sukharevskaya Sq., Moscow 129090
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Review
For citations:
Shmarina N.V., Lazareva K.E., Dmitriev I.V., Balkarov A.G., Lonshakov D.V., Zhuravel N.S., Smirnova V.V. Rare cases of primarily infected kidney graft transplantation with the development of purulent complications. Transplantologiya. The Russian Journal of Transplantation. 2024;16(3):353-363. https://doi.org/10.23873/2074-0506-2024-16-3-353-363