Results of assessing the dynamics of ophthalmological complications in chronic kidney disease patients after kidney transplantation
https://doi.org/10.23873/2074-0506-2024-16-4-438-446
Abstract
Objective. The study objective was to investigate the dynamics of opthalmological complications in the non-diabetic end-stage chronic kidney disease in patients after kidney transplantation.
Material and methods. A long-term observation was conducted to assess the changes in morphofunctional parameters of eyes in patients of the study group (after kidney transplantation, n=135 (269 eyes)) and the comparison group (continued on hemodialysis, n=81 (162 eyes)) over 18 months. Both general and specialized ophthalmological investigation methods were employed.
Results. The observation showed a positive trend in patients after kidney transplantation, which was manifested by reduced corneal and conjunctival calcification. In the comparison group, both an increase and decrease in qualitative signs of retinopathy were seen as based on optical coherence tomography data, while in the study group, most retinopathy signs decreased, indicating a positive trend possibly brought about by the kidney transplantation. Analysis of optical coherence tomography quantitative parameters showed an improvement in central choroidal thickness and retinal nerve fiber layer thickness in the study group.
Conclusion. Kidney transplantation in patients with the non-diabetic end-stage chronic kidney disease leads to a reduction in ophthalmological complications both in the anterior eye segment (reduced corneal and conjunctival calcification) and in its posterior segment (improved optical coherence tomography retinal parameters).
Supporting agencies: The study was performed without external funding
About the Authors
U. F. Mavlyanova
Republican Specialized Scientific and Practical Medical Center for Eye Microsurgery
Uzbekistan
Uzbekistan
Umida F. Mavlyanova - Cand. Sci. (Med.), Ophthalmic Surgeon, Cataract Surgery Department.
14 Kichik khalka yuli, Tashkent 100173
A. F. Yusupov
Republican Specialized Scientific and Practical Medical Center for Eye Microsurgery
Uzbekistan
Uzbekistan
Azamat F. Yusupo - Prof., Dr. Sci. (Med.), Director.
14 Kichik khalka yuli, Tashkent 100173
F. Sh. Bakhritdinov
V. Vakhidov Republican Specialized Scientific and Practical Medical Center for Surgery
Uzbekistan
Uzbekistan
Fazlitdin Sh. Bakhritdinov - Prof., Dr. Sci. (Med.), Head of the Department of Transplantology.
10 Kichik khalka yuli, Tashkent 100096
Kh. S. Ashirmatova
Republican Specialized Scientific and Practical Medical Center for Eye Microsurgery
Uzbekistan
Uzbekistan
Khatira S. Ashirmatova - Cand. Sci. (Med.), Head of In-Patient Department.
14 Kichik khalka yuli, Tashkent 100173
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Review
For citations:
Mavlyanova U.F., Yusupov A.F., Bakhritdinov F.Sh., Ashirmatova Kh.S. Results of assessing the dynamics of ophthalmological complications in chronic kidney disease patients after kidney transplantation. Transplantologiya. The Russian Journal of Transplantation. 2024;16(4):438-446. https://doi.org/10.23873/2074-0506-2024-16-4-438-446
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