The experience of bilateral lung retransplantation after prolonged extracorporeal oxygenation
E. A. Tarabrin,
M. Sh. Khubutiya,
A. S. Guseva,
E. A. Ermakova,
E. I. Pervakova,
S. V. Zhuravel,
A. M. Gasanov,
V. G. Kotandzhyan,
N. A. Karchevskaya,
T. E. Kallagov,
I. U. Ibavov,
M. S. Kevorkova,
Z. G. Berikkhanov,
M. Yu. Ivanova https://doi.org/10.23873/2074-0506-2024-16-4-491-499
Abstract
Background. Transplantation is the only effective method of helping patients with irreversible damage of the lung function when the possibilities of other treatment methods have been exhausted. At the same time, a chronic graft rejection is the main cause of the loss of the donor organ function in the long-term period, developing in more than 50% of patients within 5 years after surgery. Given irreversible lung damage with loss of lung functions, the only effective treatment method for this patient population is retransplantation, which is associated with high risks of complications and a long rehabilitation of the patient in the postoperative period.
Objective. Demonstration of the first Russian experience of bilateral lung retransplantation in a patient after a longterm extracorporeal oxygenation.
Results. The article presents the description of the first experience of bilateral lung retransplantation in Russia performed in a patient with a chronic rejection 4.5 years after the primary transplantation performed for end-stage lung lesions in non-langerhans cell histiocytosis. In the 96-day period of waiting for a donor organ, the patient's gas-exchange lung function was compensated by using veno-venous extracorporeal membrane oxygenation.
Conclusions. Retransplantation is an effective method of treatment for patients with irreversibly damaged lung function, but still remains an operation associated with high risks of complications and unfavorable outcome.
About the Authors
E. A. Tarabrin
N.V. Sklifosovsky Research Institute for Emergency Medicine; I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Evgeniy A. Tarabrin - Dr. Sci. (Med.), Senior Researcher, Department of Emergency Surgery, Endoscopy and Intensive Care, N.V. Sklifosovsky RIEM; Head of the Department of Hospital Surgery No. 2, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First MSMU (Sechenov University)
3 Bolshaya Sukharevskaya Sq., Moscow 1290908; Bldg. 2 Trubetskaya St., Moscow 119991
M. Sh. Khubutiya
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Mogeli Sh. Khubutiya - Academician of the Russian Academy of Sciences, Prof., Dr. Sci. (Med.), President.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
A. S. Guseva
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Arina S. Guseva - Student in the 6th year, N.V. Sklifosovsky Institute of Clinical Medicine.
8 Bldg. 2 Trubetskaya St., Moscow 119991
E. A. Ermakova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Ekaterina A. Ermakova - Student in the 5th year, N.V. Sklifosovsky Institute of Clinical Medicine.
8 Bldg. 2 Trubetskaya St., Moscow 119991
E. I. Pervakova
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Elza I. Pervakova - Cand. Sci. (Med.), Head of the Critical and Intensive Care Department with Dialysis Methods for Patients after Organ Transplantation.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
S. V. Zhuravel
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Sergey V. Zhuravel - Assoc. Prof., Dr. Sci. (Med.), Head of the Scientific Anesthesiology Department.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
A. M. Gasanov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Ali M. Gasanov - Dr. Sci. (Med.), Senior Researcher at the Department of Urgent Endoscopic Investigations.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
V. G. Kotandzhyan
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Vazgen G. Kotandzhyan - Head of the Thoracic Surgery Department; Thoracic Surgeon, Researcher at the Department of Emergency Surgery, Endoscopy, and Intensive Care.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
N. A. Karchevskaya
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Natalya A. Karchevskaya - Cand. Sci (Med.) Pulmonologist, Researcher at the Department of Emergency Surgery, Endoscopy, and Intensive Care.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
T. E. Kallagov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Taymuraz E. Kallagov - Cand. Sci. (Med.), Head of the Department of Thoracic Surgery at University Clinical Hospital No. 4.
8 Bldg. 2 Trubetskaya St., Moscow 119991
I. U. Ibavov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Ibragim U. Ibavov - Thoracic Surgeon, Junior Researcher at the Department of Emergency Surgery, Endoscopy, and Intensive Care.
3 Bolshaya Sukharevskaya Sq., Moscow 129090
M. S. Kevorkova
N.I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Marina S. Kevorkova - Teaching Assistant at the Department of Hospital Therapy of the Pediatric Faculty.
1 Ostrovityanov St., Moscow 117997
Z. G. Berikkhanov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Zelimkhan G. Berikkhanov - Cand. Sci. (Med.), Assistant Professor of Hospital Surgery Department No. 2.
8 Bldg. 2 Trubetskaya St., Moscow 119991
M. Yu. Ivanova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Milena Yu. Ivanova - Residency training physician, Senior Laboratory Assistant at Hospital Surgery Department No. 2.
8 Bldg. 2 Trubetskaya St., Moscow 119991
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Review
For citations:
Tarabrin E.A., Khubutiya M.Sh., Guseva A.S., Ermakova E.A., Pervakova E.I., Zhuravel S.V., Gasanov A.M., Kotandzhyan V.G., Karchevskaya N.A., Kallagov T.E., Ibavov I.U., Kevorkova M.S., Berikkhanov Z.G., Ivanova M.Yu. The experience of bilateral lung retransplantation after prolonged extracorporeal oxygenation. Transplantologiya. The Russian Journal of Transplantation. 2024;16(4):491-499. https://doi.org/10.23873/2074-0506-2024-16-4-491-499
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