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Transplantologiya. The Russian Journal of Transplantation

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MODULATION OF ANTIBODY MEDIATED LYMPHOCYTOLYSIS IN VITRO UNDER A MAGNETIC VECTOR POTENTIAL

Abstract

It is discovered that a change of a vector potential by means of a laboratory device effects on antigen-antibody reaction in lymphocytes suspension. The effect decreases lysis of lymphocytes in anti-CD3 antibodies presence and increases the destruction in anti-HLA antibodies presence. Authors propose that these effects are due to changes of antigen-antibody complexes lateral mobility and to changes of complexes  aggregates biochemical activity.

 

About the Authors

V. N. Novoseletsky
Moscow Institute of Physics and Technology, Dolgoprudny
Russian Federation


V. Yu. Abramov
FSBI “Shumakov Scientific Centre of Transplantology and Artificial Organs, Moscow
Russian Federation


V. M. Zaiko
FSBI “Shumakov Scientific Centre of Transplantology and Artificial Organs, Moscow
Russian Federation


N. B. Bogdanova
FSBI “Shumakov Scientific Centre of Transplantology and Artificial Organs, Moscow
Russian Federation


E. M. Trukhan
Moscow Institute of Physics and Technology, Dolgoprudny
Russian Federation


Review

For citations:


Novoseletsky V.N., Abramov V.Yu., Zaiko V.M., Bogdanova N.B., Trukhan E.M. MODULATION OF ANTIBODY MEDIATED LYMPHOCYTOLYSIS IN VITRO UNDER A MAGNETIC VECTOR POTENTIAL. Transplantologiya. The Russian Journal of Transplantation. 2013;(1):5-9. (In Russ.)

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ISSN 2074-0506 (Print)
ISSN 2542-0909 (Online)