Functional geometry of the left ventricle in patients after orthotopic heart transplantation in the early postoperative period
Abstract
The functional geometry of the left ventricle (LV) of heart was investigated in patients after orthotopic heart transplantation without any signs of rejection. Typical features of LV functional geometry in heart transplant recipients with uncomplicated postoperative period were indentified as compared to patients without heart disease. The authors have put forward the hypothesis about a diagnostic value of LV functional geometry parameters for a non-invasive diagnosis of graft dysfunction that would facilitate an optimum correction of treatment tactics.
About the Authors
T. V. Chumarnaya
Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences;
Ural Federal University
Russian Federation
Russian Federation
Yu. S. Alueva
Sverdlovsk Regional Clinical Hospital No. 1;
Ural State Medical University, Ekaterinburg
Russian Federation
Russian Federation
V. V. Kochmasheva
Sverdlovsk Regional Clinical Hospital No. 1;
Ural State Medical University, Ekaterinburg
Russian Federation
Russian Federation
N. F. Klimusheva
Sverdlovsk Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
A. I. Iofin
Sverdlovsk Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
A. N. Bykov
Sverdlovsk Regional Clinical Hospital No. 1
Russian Federation
Russian Federation
O. E. Solov'eva
Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences;
Ural Federal University
Russian Federation
Russian Federation
References
1. Mareev V., Ageev F.T., Arutyunov G.P., et al. Natsional'nye rekomendatsii OSSN, RKO i RNMOT po diagnostike i lecheniyu KhSN (chetvertyy peresmotr) [National guidelines of Company specialists in heart failure, Russian Society of Cardiology and Russian Scientific Medical Society of Physicians for the diagnosis and treatment of chronic heart failure (fourth revision)]. Serdechnaya nedostatochnost'. 2013; 7 (81): 379–472. (In Russian).
2. Alraies M.C., Eckman P. Adult heart transplant: indications and outcomes. Journal of thoracic disease. 2014; 6 (8): 1120–1128.
3. Stehlik J., Edwards L.B., Kucheryavaya A.Y, et al. The Registry of the International Society for Heart and Lung Transplantation: 29th Official adult heart transplant report – 2012. The Journal of heart and lung transplantation. 2012; 31 (10): 1052–1064.
4. Mills R.M., Naftel D.C., Kirklin J.K., et al. Heart transplant rejection with hemodynamic compromise: a multiinstitutional study of the role of endomyocardial cellular infiltrate. Cardiac Transplant Research Database. The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation. 1997; 16 (8): 813–821.
5. Mingo-Santos S., Moñivas-Palomero V., Garcia-Lunar I. Usefulness of Two- Dimensional Strain Parameters to Diagnose Acute Rejection after Heart Transplantation. Journal of the American Society of Echocardiography. 2015; 28 (10): 1149–1156.
6. Markhasin V., Solov'eva O., Chumarnaya T., Sukhareva S. Problema neodnorodnosti miokarda [Myocardial heterogeneity problem]. Rossiyskiy fiziologicheskiy zhurnal im IM Sechenova. 2009; 95 (9):919–943. (In Russian).
7. Chumarnaya T., Solov'eva O.E., Sukhareva S.V., et al. Prostranstvenno-vremennaya neodnorodnost' sokrashcheniya stenki levogo zheludochka v norme i pri ishemicheskoy bolezni serdtsa [Spatiotemporal heterogeneity of contraction of the left ventricle in normal and ischemic heart disease]. Rossiyskiy fiziologicheskiy zhurnal im IM Sechenova. 2008; 94 (11): 1217–1239. (In Russian).
8. Passino C., Barison A., Vergaro G., et al. Markers of fibrosis, inflammation, and remodeling pathways in heart failure. Clinica Chimica Acta. 2015; 443: 29–38.
9. Markhasin V.S., Chestukhin V.V., Gol'berg S.I., et al. Vklad segmentarnoy neodnorodnosti miokarda stenok levogo zheludochka v ego sokratitel'nuyu i nasosnuyu funktsiyu [Contribution segmental inhomogeneity of the left ventricular wall infarction in its contractile and pump function]. Rossiyskiy fiziologicheskiy zhurnal im IM Sechenova. 1994; 80 (4): 72–74. (In Russian).
10. Anderson B., ed. Echocardiography: the normal examination and echocardiographic measurements. Wiley-Blackwell, 2002. 251 p.
11. Gibson D.G., Brown D.J. Continuous assessment of left ventricular shape in man. Br Heart J. 1975; 37 (9): 904–910.
12. Di Donato M., Dabic P., Castelvecchio S., et al. Left ventricular geometry in normal and post-anterior myocardial infarction patients: sphericity index and 'new' conicity index comparisons. Eur J Cardiothorac Surg. 2006; 29 Suppl 1: S225–230.
13. Kass D.A., Traill T.A., Keating M., et al. Abnormalities of dynamic ventricular shape change in patients with aortic and mitral valvular regurgitation: assessment by Fourier shape analysis and global geometric indexes. Circ Res. 1988; 62 (1): 127–138.
Review
For citations:
Chumarnaya T.V., Alueva Yu.S., Kochmasheva V.V., Klimusheva N.F., Iofin A.I., Bykov A.N., Solov'eva O.E. Functional geometry of the left ventricle in patients after orthotopic heart transplantation in the early postoperative period. Transplantologiya. The Russian Journal of Transplantation. 2016;(2):9-15.
Views:
785
