Первая успешная трансплантация тонкой кишки в Институте скорой помощи им. Н.В. Склифосовского

Статья посвящена описанию первого наблюдения успешной трансплантации тонкой кишки (ТТК) в Институте скорой помощи им. Н.В. Склифосовского. Содержит краткий обзор литературы по основным проблемам ТТК, описание истории болезни донора, особенностей проведения наркоза, операции и течения послеоперационного периода, включая тактику иммуносупрессии, диагностики и лечения развившихся осложнений. Подробно описаны результаты морфологического контроля за развитием реакции отторжения, приведены данные УЗ-наблюдения за изменениями трансплантированной кишки по ходу ее адаптации к новым условиям, тактика парентерального и энтерального питания.

1. Carrel, A. The transplantation of organs. A preliminary communication / А. Carrel // J. Am. Med. Assoc. – 1905. – Vol. 45. – P. 1645.

2. Lillehei, R. The physiological response of the small bowel of the dog to ischemia including pro-longed in vitro preservation of the bowel with successful replacement and survival / R. Lillehei, B. Goott, F. Miller // Ann. Surg. –1959. – Vol. 150, N 4.– P. 543–559.

3. Transplantation of stomach, intestine, and pancreas: experimental and clinical observation / R.C. Lillehei, Y. Idezuki, J.A. Feemster [et al.] // Surgery. – 1967. – Vol. 62. – P. 721–741.

4. Pritchard, T.J. Small bowel transplantation / T.J. Pritchard, R.L. Kirkman // World J. Surg. – 1985. – Vol. 9. – P. 860–867.

5. Fishbein, T.M. Intestinal Transplantation / T.M. Fishbein // N. Engl. J. Med.– 2009. – Vol. 361, N 10. – P. 998–1008.

6. Stuart, F.P. Organ Transplantation / F.P. Stuart, M.M. Abecassis,D.B. Kaufman. – 2nd ed. – New York: Landes Bioscience, 2003. – 618 p.

7. Howard, L. Current use and clinical outcome of home parenteral and enteral nutrition therapies in the United States / L. Howard, M. Ament, C.R. Fleming [et al.] // Gastroenterology. – 1995. – Vol. 109, N 2. – P. 355–365.

8. Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome / B. Messing, P. Crenn, P. Beau // Gastroenterology.– 1999.– Vol. 117, N 5.– P. 1043–1050.

9. Survival of home parenteral nutritiontreated patients: 20 years of experience at the Mayo Clinic / J.S. Scolapio, C.R. Fleming, D.G. Kelly // Mayo Clin. Proc. – 1999. – Vol. 74, N 3. – P. 217–222.

10. Howard, L. Current statusof home parenteral nutrition in the United States / L. Howard, M. Malone // Transplant. Proc. – 1996. – Vol. 28, N 5. – P. 2691–2695.

11. Abdominal Multiviscereal Transplantation / S. Todo, A. Tzakis, K. Abu-Elmagd [et al.] // Transplantation. – 1995. – Vol. 59, N 2. – P. 234–240.

12. Bacterial translocation is enhanced in pig intestinal transplantation when the colon is included in the graft / M. Spada, M. Alessiani, M. Fabbi [et al.] // Transplant. Proc. – 1996. – Vol. 28, N 5. – P. 2658–2659.

13. Mycophenolate mofetil as primary and rescue therapy in intestinal transplantation / A. Tzakis, D. Weppler, M. Khan [et al.] // Transplant Proc. – 1998. – Vol. 30, N 6. – P. 2677–2679.

14. 51Cr-EDTA: a marker of early intestinal rejection in the rat / D. Grant,D. Lamont, R. Zhong [et al.] // J. Surg. Res. – 1989. – Vol. 46, N 5. – P. 507–514.

15. Diagnosis of intestinal transplant rejection using 99mtechnetium-DTPA / A.M. D’Alessandro, M. Kalayoglu, R. Hammes [et al.] // Transplantation. – 1994. – Vol. 58, N 1. – P. 112–113.

16. Infectious complications after small bowel transplantation in adults: and update / S. Kusne, H. Furukawa, K. Abu- Elmagd [et al.] // Transplant. Proc. –1996. – Vol. 28, N 5. – P. 2761–2762.

17. Farmer, R.G. Long-term followup of patients with Crohn’s disease / R.G. Farmer, G. Whelan, V.W. Fazio // Gastroenterology. – 1985. – Vol. 88, N 6. –P. 1818–1825.

18. Successful treatment for homozygous protein C deficiency by hepatic transplantation / J.F. Ca-sella, J.H. Lewis, F.A. Bontemps [et al.] // Lancet. – 1988. – Vol. 1, N 8553. – P. 435–438.

19. Intestinal and multiple organ transplantation / J. Reyes, R. Selby, K. Abu-Elmagd [et al.] // Textbook of Critical Care. – 4th ed. – Orlando: WB Saunders Company, 2000. – P. 1986– 1997.

20. Winter HS. Intestinal polyps // Pediatric Gastrointestinal Disease: Pathophysiology, Diagnosis, Managemen / eds. W.A. Walker, P.R. Durie, J.R. Hamilton [et al.]. – 2nd ed. – BC Decker, 1996. – P. 891–906.

21. A case of beriberi accompanying short bowel / K. Hiroi, Y. Goto, J. Ishikawa [et al.] // Acta Paediat. Jpn. – 1995. – Vol. 37, N 1. – P. 84–87.

22. Hove, H. Colonic lactate metabolism and D-lactic acidosis / H. Hove, P.B. Mortensen // Dig. Dis. Sci. – 1995. – Vol. 40, N 2. – P. 320–330.

23. Malposition of a implantable venous access catheter in the azygos vein: report of a case / S. Ikeda, Y. Sera, H. Yamamoto // Surg. Today. – 1995. – Vol. 25, N 7. – P. 649–650.

24. Jenkins, R.C. Growth hormone therapy for protein catabolism / R.C. Jenkins, R.J. Ross // QJM. – 1996. – Vol. 89, N 11. – P. 813–819.

25. Small bowel and liver/small bowel transplantation in children / J. Reyes,A.G. Tzakis, S. Todo // Semin. Pediatr. Surg. – 1993. – Vol. 2, N 4. – P. 289–300.

26. Current status of intestine transplantation in children / J. Reyes, J. Bueno, S. Kocochis [et al.] // J. Pediatr. Surg. – 1998. – Vol. 33, N 2. – P. 243–254.

27. The many faces of multivisceral transplantation / T.E. Starzl, S. Todo,A. Tzakis [et al.] // Surg. Gynecol. Obstet. – 1991. – Vol. 172, N 5. – P. 335–344.

28. Technical aspects of intestine transplantation / H. Furukawa, K. AbuElmagd, J. Reyes [et al.] // Surgical Technology International / eds. M.H. Braverman, R.L. Tawes. – Vol. 3. – San Francisco: University Medical Press,1994. – P. 165–170.

29. Clinical intestine transplantation new perspectives and immunologic considerations / K.M. Abu-Elmagd, J. Reyes, S. Todo [et al.] // J. Am. Coll.Surg. – 1998. – Vol. 186, N 5. – P. 512–527.

30. Current status of intestinal transplantation in children / J. Reyes, J. Bueno, S. Kocoshis [et al.] // J. Pediatr. Surg. – 1998. – Vol. 33, N 2. – P. 243–254.

31. Infectious complications after small bowel transplantation in adults / S. Kusne, R. Manez, H. Bonet [et al.] // Transplant. Proc. – 1994. – Vol. 26, N 3. – P. 1682–1683.

32. Three years clinical experience with intestinal transplantation / K. AbuElmagd, S. Todo, A. Tzakis [et al.] // J. Am. Coll. Surg. – 1994. – Vol. 179, N 4. – P. 385– 400.

33. Wells, C.L. Colonization and translocation of intestinal bacterial flora / C.L. Wells // Transplant. Proc. – 1996. – Vol. 28, N 5. – P. 2653–2656.

34. Infectious complications after small bowel transplantation in adults: an update / S. Kusne, H. Furukawa, K. Abu-Elmagd [et al.] // Transplant. Proc. – 1996. – Vol. б28, N 5. – P. 2761–2762.

35. Berg, R.D. Promotion of the translocation of enteric bacteria from the gastrointestinal tract of mice by oral treatment with penicillin, clindamicyn or metronidazole / R.D. Berg // Infect. Immun. – 1981. – Vol. 33, N 3. – P. 854–861.