Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors
https://doi.org/10.23873/2074-0506-2018-10-2-87-97
Abstract
Donor organ shortage stimulated an active use of donors with expanded evaluation criteria. The main evaluation method was a histological examination of liver graft biopsy specimens before (time-zero biopsy) and after reperfusion (time-1 biopsy). Severe ischemic and reperfusion injuries among recipients who received a liver graft made 20.4% and 16.6% respectively. The study showed no impact of small droplet, medium droplet, or even large droplet steatosis (less than 50%) on graft reperfusion injury.
About the Authors
M. Sh. Khubutiya
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
Mogeli Sh. Khubutiya - Acad. of RAS, Professor, President of N.V. Sklifosovsky RIEM.
3 Bolshaya Sukharevskaya Square, Moscow 129090
L. N. Zimina
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
I. E. Galankina
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
V. A. Gulyaev
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
M. S. Novruzbekov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
O. D. Olisov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
K. M. Magomedov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation
Russian Federation
3 Bolshaya Sukharevskaya Square, Moscow 129090
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Review
For citations:
Khubutiya M.Sh., Zimina L.N., Galankina I.E., Gulyaev V.A., Novruzbekov M.S., Olisov O.D., Magomedov K.M. Morphofunctional evaluation of liver grafts obtained from standard donors and expanded criteria donors. Transplantologiya. The Russian Journal of Transplantation. 2018;10(2):87-97. https://doi.org/10.23873/2074-0506-2018-10-2-87-97
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