Drug-induced liver injuries (part I)
https://doi.org/10.23873/2074-0506-2011-0-1-13-21
Abstract
The paper describes current ideas on the mechanisms, classification, diagnosis, and treatment of drug-induced liver injuries (DILI). The latter masks all known acute and chronic liver diseases. Drugs are one of the leading causes of fulminant hepatic failure in many countries of the world. Early diagnosis and timely discontinuation of a drug that causes liver damage allow the disease progression to be prevented. The bases of DILD diagnosis are the careful collection of drug history data, the exclusion of other possible causes of liver damage, and the application of diagnostic scales (CIOMS/RUCAM).
About the Author
S. F. Galimova
V.Kh. Vasilenko Clinic of Internal Propedeutics, Gastroenterology, and Hepatology, I.M. Sechenov, First Moscow State Medical University
Russian Federation
Russian Federation
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For citations:
Galimova S.F. Drug-induced liver injuries (part I). Transplantologiya. The Russian Journal of Transplantation. 2011;(1):13-21. (In Russ.) https://doi.org/10.23873/2074-0506-2011-0-1-13-21
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