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The use of telaprevir for the treatment of hepatitis C in patients undergoing liver transplantation (Literature review and clinical experience)

Abstract

Authors reviewed published data concerning antiviral treatment of liver transplant recipients with 1st generation HCV protease inhibitors (telaprevir and boceprevir). Efficacy and adverse events have been analyzed with peculiar attention to drug-drug interactions between calcineurin inhibitors and HCV protease inhibitors. The article is illustrated with clinical cases.

About the Authors

M. Sh. Khubutiya
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
Russian Federation


V. E. Syutkin
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
Russian Federation


N. I. Geyvandova
Stavropol State Medical University
Russian Federation


A. A. Salienko
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
Russian Federation


T. V. Gudzovskaya
Stavropol Regional Clinical Hospital
Russian Federation


M. S. Novruzbekov
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
Russian Federation


References

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Review

For citations:


Khubutiya M.Sh., Syutkin V.E., Geyvandova N.I., Salienko A.A., Gudzovskaya T.V., Novruzbekov M.S. The use of telaprevir for the treatment of hepatitis C in patients undergoing liver transplantation (Literature review and clinical experience). Transplantologiya. The Russian Journal of Transplantation. 2015;(1):13-22.

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ISSN 2074-0506 (Print)
ISSN 2542-0909 (Online)