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Endoscopic control after retroperitoneal pancreas transplantation with a Roux-en-Y duodenojejunostomy for exocrine drainage

https://doi.org/10.23873/2074-0506-2024-16-2-209-218

Abstract

Background. Simultaneous pancreas and kidney transplantation is a gold standard in the treatment of diabetes mellitus complicated by stage 5 chronic kidney disease as a result of diabetic nephropathy. One of the main problems of clinical pancreas transplantation is the pancreas graft exocrine drainage. In order to preserve the advantages of the retroperitoneal graft location and avoid the main disadvantage of duodenal drainage, namely, fatal complications potentially arising in case of necessary graft removal, we have proposed a modified method of retroperitoneal pancreatic transplantation with exocrine drainage via a modified Roux-en-Y duodenojejunostomy. It reduces the number of severe surgical complications and increases the recipient survival rate. When this method was used in previous years, it was not possible to assess the condition of donor duodenum mucosa and interintestinal anastomoses.

Objective. To demonstrate the possibility of endoscopic assessment of interintestinal anastomoses when performing retroperitoneal pancreas transplantation with small intestine drainage of exocrine secretions.

Results. The article presents the initial experience of endoscopic assessment of the interintestinal anastomoses and the mucous membrane of the donor duodenum after retroperitoneal pancreas transplantation with exocrine drainage via a Roux-en-Y duodenojejunostomy.

Conclusion. The presented case demonstrates the feasibility of diagnostic endoscopic interventions when performing retroperitoneal pancreas transplantation with small intestine drainage of pancreatic secretions.

About the Authors

N. S. Zhuravel
N.V. Sklifosovsky Research Institute for Emergency Medicine; Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of Medicine
Russian Federation

Nikita S. Zhuravel,  Cand. Sci. (Med.), Surgeon, Junior Researcher of Department of Kidney and Pancreas Transplantation; Assistant Professor of the Department of Transplantology and Artificial Organs 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 

4 Dolgorukovskaya St., Moscow 127006 



A. G. Balkarov
N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University; Research Institute for Healthcare Organization and Medical Management
Russian Federation

Aslan G. Balkarov, Cand. Sci. (Med.), Head of the Scientific Department of Kidney and Pancreas Transplantation; Associate Professor of the Department of Transplantology and Artificial Organs; Head of the Organizational and Methodological Department for Transplantology

3 Bolshaya Sukharevskaya Sq., Moscow 129090 

1 Ostrovityanov St., Moscow 117997 

30 Bolshaya Tatarskaya St., Moscow 115184 



R. V. Storozhev
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation

Roman V. Storozhev, Surgeon of Department of Kidney and Pancreas Transplantation

3 Bolshaya Sukharevskaya Sq., Moscow 129090 



Yu. A. Anisimov
N.V. Sklifosovsky Research Institute for Emergency Medicine; Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of Medicine
Russian Federation

Yuriy A. Anisimov, Cand. Sci. (Med.), Surgeon of Department of Kidney and Pancreas Transplantation; Associate Professor of Department of Transplantology and Artificial Organs 

3 Bolshaya Sukharevskaya Sq., Moscow 129090 

4 Dolgorukovskaya St., Moscow 127006 



A. S. Kondrashkin
N.V. Sklifosovsky Research Institute for Emergency Medicine; Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of Medicine
Russian Federation

Alexander S. Kondrashkin, Cand. Sci. (Med.), Deputy Chief Physician for Internal Quality Control of Medical Care of Department of Kidney and Pancreas Transplantation; Associate Professor of the Department of Transplantology and Artificial Organs

3 Bolshaya Sukharevskaya Sq., Moscow 129090 

4 Dolgorukovskaya St., Moscow 127006 



D. V. Lonshakov
N.V. Sklifosovsky Research Institute for Emergency Medicine
Russian Federation

Denis V. Lonshakov, Surgeon of Department of Kidney and Pancreas Transplantation

3 Bolshaya Sukharevskaya Sq., Moscow 129090 



N. V. Shmarina
N.V. Sklifosovsky Research Institute for Emergency Medicine; N.I. Pirogov Russian National Research Medical University
Russian Federation
Nonna V. Shmarina, Senior Researcher of Department of Kidney and Pancreas Transplantation, N.V. Sklifosovsky Research Institute for Emergency Medicine, Associate Professor of the Department of Transplantology and Artificial Organs

3 Bolshaya Sukharevskaya Sq., Moscow 129090 

1 Ostrovityanov St., Moscow 117997 



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For citations:


Zhuravel N.S., Balkarov A.G., Storozhev R.V., Anisimov Yu.A., Kondrashkin A.S., Lonshakov D.V., Shmarina N.V. Endoscopic control after retroperitoneal pancreas transplantation with a Roux-en-Y duodenojejunostomy for exocrine drainage. Transplantologiya. The Russian Journal of Transplantation. 2024;16(2):209-218. https://doi.org/10.23873/2074-0506-2024-16-2-209-218

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ISSN 2074-0506 (Print)
ISSN 2542-0909 (Online)