The patient in the remote period after cadaveric kidney allotransplantation developed leukopenia, which required a dose reduction of immunosuppressive drugs. The transplant rejection crisis developed against this background. Thus, the presence of leukopenia in a patient after cadaveric kidney allograft transplantation requires detecting early signs of
not only infectious complications, but also a crisis of rejection.

This article is a part of a public report of the survey carried out by the Levada-Center, dedicated to the study of the problems of organ donation in Russia. On the basis of a nationwide survey of public opinion the author analyzes views and positions of Russians in relation to organ donation.

The clinical example illustrates the use of microdialysis techniques for assessing function of the kidney allotransplantat in the early postoperative period. Microdialysis allows to evaluate metabolic changes in the interstitial space of the graft in real-time mode.

Extremely large ethical importance of ascertaining death based on neurological criteria sets the highest benchmark for the accuracy, speed and security of diagnostics. In most cases, the clinical picture of the death of brain is complicated by face injuries, spontaneous or induced automatisms, inability to carry out an isolation test safely. The modern trend
is to use additional confirmatory tests in difficult cases. A significant reduction of the observation time or complete rejection of the re-examination are discussing in the world literature. With the increased number of donor centers and the growing sense of ethical and economical unreasonableness of a futile resuscitation, modern, evidence-based legislative scheme of brain death diagnosis is very important.