Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
https://doi.org/10.23873/2074-0506-2010-0-1-61-67
Abstract
The paper provides a brief overview of the data available in the literature with the discussion of the basic principles of the diagnosis and treatment of a graft-versus-host reaction (GVHR). After orthotopic liver transplantation, the incidence of this complication is 1–3%, mortality is as high as 75%. The paper describes a case of GVHR after liver transplantation, the clinical picture of which shows a preponderance of skin manifestations. Timely diagnosis of this rare complication has allowed the patient to be effectively treated.
About the Authors
Yu. V. Skvortsova
Federal Research Clinical Center of Pediatric Hematology, Oncology, and Immunology;
Russian Pediatric Clinical Hospital
Russian Federation
Bone Marrow Transplantation Unit
Russian Federation
Bone Marrow Transplantation Unit
O. D. Olisov
N.V. Sklifosovsky Research Institute of Emergency Care
Russian Federation
Department of Renal Transplantation
Russian Federation
Department of Renal Transplantation
V. E. Syutkin
N.V. Sklifosovsky Research Institute of Emergency Care
Russian Federation
Department of Renal Transplantation
Russian Federation
Department of Renal Transplantation
D. M. Konovalov
Federal Research Clinical Center of Pediatric Hematology, Oncology, and Immunology;
Russian State Medical University
Russian Federation
Russian Federation
A. V. Chzhao
N.V. Sklifosovsky Research Institute of Emergency Care
Russian Federation
Department of Renal Transplantation
Russian Federation
Department of Renal Transplantation
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Review
For citations:
Skvortsova Yu.V., Olisov O.D., Syutkin V.E., Konovalov D.M., Chzhao A.V. Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature. Transplantologiya. The Russian Journal of Transplantation. 2010;(1):61-67. (In Russ.) https://doi.org/10.23873/2074-0506-2010-0-1-61-67
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