Analysis of kidney transplantation results in patients with chronic renal disease

Introduction. The number of patients with chronic kidney disease has been steadily increasing throughout the world, which makes this pathology a pressing problem.

The purpose. The analysis of heterotopic kidney transplantation results.

Material and methods. The authors analyzed the experience of the clinical work arrangement, the results of operations, assessed the complication rate and the quality of life in 133 patients after heterotopic cadaveric kidney transplantation performed in the Grodno regional clinical hospital in the period from 2013 to mid August of 2018.

Results. In the early postoperative period, complications occurred in 22 (13.5 %) patients, the postoperative mortality was 1.8% (3 patients). In the late postoperative period, the kidney explantation was performed in 4 (2.45%) patients, 6 patients died (3.7%) as a result of progressing comorbidities and complications (average at 15.6±9.8 months after transplantation). A 5-year predicted patient survival after heterotopic kidney transplantation calculated by using the Kaplan-Meier' method was 94.5%.

Conclusions. Kidney transplantation in the Grodno Region, the results of operations, graft survival, quality of life and patient survival are comparable to international standards. A careful selection, examination, and preparation of patients for transplantation have a great effect on treatment outcomes.

1. Doria C., Margetich L. Recipient Kidney Transplantation Surgery. In: Ramirez C.J.B., McCauley J., eds. Contemporary Kidney Transplantation. Philadelphia: Springer Nature, 2017. 91–101.

2. Gautier S.V., ed. Transplantology and artificial organs. Moscow: Laboratoriya znaniy Publ., 2018. 180–192. (In Russian).

3. Danovich G.M. Kidney transplantation. [In Russian: Moysyuk Ya.G., ed., tr. 5th ed. Moscow: GEOTAR-Media Publ., 2014. 23–53]. (In Russian).

4. Cernaro V., Tripepi G., Visconti L., et al. Convective Dialysis Reduces Mortality Risk: Results from a Large Observational, Population-Based Analysis. Therapeutic Apheresis and Dialysis. 2018;22(5):457–468. PMID:29992748 DOI:10.1111/1744-9987.12684

5. Savitskiy S.E., Snezhitskiy V.A., Batvinkov N.I., et al. Kidney transplantation in the Grodno region. Journal of the Grodno State Medical University. 2013;3(43):102–104. (In Russian).

6. Matevosyan E., Snopok Yu., Doll’ D. Clinical aspects of kidney transplantation. Vestnik VGMU. 2015;14(6):53–63. (In Russian).

7. Vistoli F., Perrone V., Amorese G., Boggi U. Kidney Transplant Recipient Surgery. Ch. 9. In: Orlando G., Remuzzi G., Williams D.F., eds. Kidney Transplantation, Bioengineering and Regeneration. Oxford: Academic press, 2017. 111–126.

8. Al-Khafaji A. ICU Care of Abdominal Organ Transplant Patients. Oxford University Press, 2013. 157–167.

9. Watson C.J.E., Friend P.J. Surgical techniques of kidney transplantation. In: Morris P.J., Knechtle S.I., eds. Kidney transplantation: principles and practice. 7th ed. New York: Elsevier, 2014. 161–175.