EDITORIAL
PROBLEMATIC ASPECTS
Relevance. Timely diagnosis and treatment of postoperative complications after pancreas transplantation is an actual problem of modern clinical transplantation.
Purpose. The assessment of the endoscopy potential for the diagnosis and correction of postoperative complications after pancreas transplantation.
Materials and methods. Since October 2011, simultaneous retroperitoneal pancreas-kidney transplantation has been performed in 27 patients. In 8 cases, the use of endoscopic techniques allowed a timely identification and treatment of the complications occurred.
Conclusions. Endoscopic techniques proved to be highly efficient in the diagnosis and treatment of surgical complications and immunological impairments after retroperitoneal pancreas transplantation.
The article describes a lyophilized sterile allograft made of bone tissue, and its implementation as a medical device in the practice of reconstructive surgery.
Possessing an osteoconductive effect, the graft helps to restore the structure of a damaged bone, and accelerates the regeneration of bone defects. According to the RF Government Regulation No. 1416 of 27.12.2012, the product has to pass the authorization procedure including the conduct of specific technical, toxicological, and clinical trials to be certified by Roszdravnadzor for clinical use.
In the Department of Kidney Transplantation of Petrovsky National Research Centre of Surgery, the investigations of kidney biopsy specimens for С4d started in 2009. The study was performed in 119 patients with impaired function of kidneys allografted from living related donors. The staining for C4d was negative in 85 cases, and positive in 34 cases. The groups were compared on the following parameters: the patient mortality, and allograft loss. Besides, morphologic findings in the biopsy were compared by nature between the groups. There were 6 deaths among 85 patients in Group 1, and 16 deaths among 34 patients in Group 2. Comparative analysis of results, using Fischer's criterion, demonstrated a statistically significant difference in mortality between the groups ( 2 = 4,86, p = 0,0275). As for graft losses, and the nature of assessed morphology findings, they were nearly similar in both groups. Therefore, according to our data, the presence of C4d protein was associated with increased mortality. The differences between the groups in all other parameters were not statistically significant.
Describes a case of successful treatment of acute destructive calculous cholecystitis after bilateral lung transplantation.
REVIEW ARTICLES AND LECTURES
The authors studied the world experience in technologies and devices for the donor organ storage, the current status and prospects, innovative developments. The status of the issue in Russia and the CIS countries was specifically reviewed. The need in special devices for the donor organ storage was assessed using a donor heart as an example.
The article reviews the current methods and indications for the use of allograft skin in the management of burns, as well as the prospects for application of the allografts in tissue engineering.
HISTORY OF MEDICINE
DATES AND EVENTS
ISSN 2542-0909 (Online)